Manganese
What function does it perform, in critical metabolic events in human biology?
Manganese acts as a co-factor to nearly all classes of enzymes such as hydrolases (phosphohydrolase), transferases (phosphotransferase), ligases, lyases, oxido-reductases, kinases and decarboxylase. It also helps in the synthesis of mucopolysaccharides, proteoglycans and glycoproteins. It can also mediate reactions as a metalloenzyme (Medeiros & Wildman, 2015; Gropper & Smith, 2013). While manganese can be replaced by magnesium in some of the catalytic reactions, two reactions in the synthesis of connective tissue pathway, namely, the activation of xylosyl transferase and glycosyl transferase or galactosyl transferase, are specifically manganese–dependent. These ...
