Summary: In the article titled, “Abnormal Cortex Plasticity in Juvenile Myoclonic Epilepsy”, the authors investigate the role of defective motor plasticity in the pathogenesis of Juvenile Myoclonic Epilepsy (Strigaro et al.). Prior to this study, JME was linked to motor cortex hyper-excitability and to the abnormal function of thalamic networks. This study, identifies a new mechanism that can cause JME, a common form of generalized epilepsy seen in children. The motor cortex plasticity was studied using an interesting technique called the Paired Associated Stimulation (PAS). The details of this technique are discussed in the methodology section. The role of ...
Motor Cortex College Essays Samples For Students
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Summary of the article
This article is about a study that was conducted to check the abnormal short latency synaptic plasticity in the motor cortex of subjects with Becker muscle dystrophy (BMD). Before the research could take place, the author indicates that the assessment of the cortical function especially with patients with BMD has brought about contradicting results. The researchers used the repetitive transcranial magnetic stimulation (rTMS) so as to explore the excitability of the motor cortex. Therefore, the participants of the study were thirteen patients suffering from Becker Muscle dystrophy. Out of the thirteen patients, six of them are stated to have ...
Fatigue
Fatigue is a common condition suffered by individuals undergoing chronic illness. The two main factors responsible for fatigue include central and peripheral mechanisms. Central mechanisms largely arise from proximal events such as neuromuscular junction, which is subdivided into supraspinal or spinal. Peripheral fatigue is caused by muscle contraction activities and includes excitation contraction or muscle bioenergetics. The discussion covers some mechanisms involved in fatigue experiences (Gandevia, 1994).
Voluntary muscle activation
This mechanism associated with central fatigue, accounts for about 15% to 20% of the usual and normal fatigue during continuous or sustained fatigue contraction. The voluntary drive of the muscle incurs difference in ...
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Parkinson’s disease was first described by James Parkinson in 1817 as the “shaking palsy”. A person with Parkinson’s disease suffers from continuous shaking tremors while they are at rest, a phenomenon known as “pill rolling” (Jankovic, 2008). There are several public figures that live with Parkinson’s disease including the actor Michael J. Fox, the boxer Muhammad Ali, and former Attorney General Janet Reno. While tremendous research efforts have uncovered many important aspects of this disease, it is still unclear what determines the onset of this disease. The majority of Parkinson disease cases are idiopathic, meaning that there ...
