Sickle-Cell Anemia College Essays Samples For Students

Sickle cell anemia is an inherited disorder of the blood where the red blood cells form an abnormal crescent shape. The Red blood cells deliver oxygen from the lungs to the body tissues are generally flexible and round, facilitating them to move easily through the blood vessels. Nevertheless, in individuals with sickle cell anemia, the texture and shape of the red blood cells can vary. They turn out to be sticky, hard and take the shape of a disc. The cells die prematurely, resulting to a deficiency of red blood cells (David, 2011).
Sickle cell anemia is passed through families ...

The differences between the oxygenated and deoxygenated states of hemoglobin

Erythrocytes of the blood act as carriers of hemoglobin; a four unit protein that through binding process with oxygen molecules, thereby forming oxyhemoglobin, transports oxygen to various part of an animal’s body. Oxygenated and deoxygenated states of hemoglobin have different quaternary structure. The disparity in quaternary structures of these two kinds of hemoglobin is attributed to the binding of oxygen with hemoglobin. The beta chains in oxygenated hemoglobin are much closer to each other compared to the ones in the deoxygenated hemoglobin (Campbell &Farrell, 2009). In the same light, the quaternary structure is affected by the hemoglobin’s ...

Analytical extended definition

Sickle cell anemia is a disease that affects hemoglobin in people. It mainly affects Africans and people from the Mediterranean and Middle East. Hemoglobin is found in the red blood cells and carries oxygen throughout the body, so people suffering from the disease do not get enough oxygen in the body due to lack of hemoglobin. The disease changes the shape of the red blood cells into sickle-shape thus the origin of the word sickle cell. Normal red blood cells are flexible and have the shape of a disc while the sickle-shaped ones are shaped like a crescent. The disease is also ...

The differences between the oxygenated and deoxygenated states of hemoglobin

a. Red Blood Cell with oxygenated hemoglobin (diamagnetic) has no effect on the magnetic field
b. Deoxygenated Red Blood Cell with deoxygenated hemoglobin which is paramagnetic affects magnetic field
Erythrocytes of the blood act as carriers of hemoglobin; a four unit protein that through binding process with oxygen molecules, thereby forming oxyhemoglobin, transports oxygen to various part of an animal’s body. Oxygenated and deoxygenated states of hemoglobin have different quaternary structure. The disparity in quaternary structures of these two kinds of hemoglobin is attributed to the binding of oxygen with hemoglobin. The beta chains in oxygenated hemoglobin ...

Child and adolescent health issues require extra concentration due to the fact that an early disease can lead to an improper growth which may impact the entire life of a person and therefore it is important to ensure that childhood and adolescence diseases are looked after with extreme care in order to improve the quality of life and the growth of the patients. Sickle cell anemia is one of the widely studied subjects today, considering that it can cause acute chronic conditions which include severe pain and organ dysfunctional ties and has a high fatality rate. This disease is also known ...

Sickle cell anemia is a genetic disease, passed on from parents to children along the generations. It is a condition which causes severe pain and anemia. It happens when the body lacks healthy red blood cells to circulate oxygen in the body. The usual shape of the red blood cells is round, and they are flexible so they can pass through the narrow blood vessels of the body. However, sickle cell anemia causes them to become sickle-shaped, like tiny crescents, which are sticky and inflexible. This restricts their movement in the blood vessels causing them to get stuck in ...

Coursename
Sickle-cell anemia is a genetic blood disorder, which affects the red blood cells. It was first described in the medical literature in 1846. In 1910, Ernest Irons became first to write about the pathologically altered red blood cells of the patient with sickle-cell anemia (Serjeant 425-429). It is caused by the mutation of the gene encoding the synthesis of the hemoglobin. As a result, the hemoglobin of the affected people is defective (hemoglobin S). Glutamic acid in it is substituted with valine in the sixth position of the β-chain. This change greatly reduces the solubility of hemoglobin in ...

Sickle cell anemia is the most widely inherited genetic disorder in the United States. Folic acids are one important nutrient that helps increase and produce some red blood cells in the bone marrow. This paper investigates how folic acid has used a supplement for pregnant women (Knott).
Sickle cell anemia can be genetically passed to the baby from a mother who has it or who is a carrier. Symptoms of the disease include headaches, irritability, fatigue, dizziness, diarrhea, cold feeling, difficulty when breathing, difficulty concentrating and pale skin (Lindenbaum, John, & Klipstein 16).
Malnutrition in pregnant females is the main ...

Sickle cell anemia is the most widely inherited genetic disorder in the United States. Folic acids are one important nutrient that helps increase and produce some red blood cells in the bone marrow. This paper investigates how folic acid has used a supplement for pregnant women.
Sickle cell anemia can be genetically passed to the baby from a mother who has it or who is a carrier. Symptoms of the disease include headaches, irritability, fatigue, dizziness, diarrhea, cold feeling, difficulty when breathing, difficulty concentrating and pale skin ( Lindenbaum, John, and Klipstein ,16 ).
Malnutrition in pregnant women is the commonest ...

Abstract

In the last century, the knowledge of molecular biology has increased, opening new opportunities for addressing different diseases that have been affecting all populations. Before, genome and proteomic studies were seen as complicated field due to inability to get significance understanding of disease components at the molecular level. However, with the expansion of molecular biology, different techniques and tools have been developed to aid diagnosis and treatment of diseases. In this study, these tools have been investigated to understand how the knowledge on molecular diagnosis helps in detection and treatment of diseases. This study focused on the application of ...

Digestion in human beings and other animals is overly dependent on the action of enzymes; in their basic form, enzymes are protein materials that act as catalysts with the ability to produce certain chemical changes. Digestion of food substances usually begin in the mouth. The glands in the mouth produce enzyme salivary amylase (which acts on starch changing it into sugar) and lingual lipase (which kicks off the digestion of lipids) (Chiras 109). The stomach n its part, produces two enzymes, pepsin that breaks down proteins into peptides (Chiras 109). While there are no enzymes produced in the large ...

Recent studies have shown that mouse and human fibroblasts can be re-encoded into an advanced stem cell–like state when a combination of transcription aspects is introduced. Conversely, the salutary probable of induced pluripotent stem cells have remained indefinite. One of the things that make this article interesting is that it explores how the mice can be salvaged after uprooting by use of cultivated sickle cell anemia mouse model. This article also exclusively stipulates how this was achieved after rectification of the human, sickle hemoglobin. The article also presents the major goal of human therapy, which is developed, using methods ...

Orphan Drug

Introduction
The main purpose for the enactment of the U.S. Orphan Drug Act (ODA) of 1983 is to conduct a research on some of the rare diseases whose medical needs remain to be unresolved.
The law has given incentives to various sponsors who have tried to develop therapies for some of the rare medical conditions that can affect at least 200,000 individuals on a yearly basis (Premiere Research 1). For this study, the objective is to create a regulatory strategy or path for Orphan Drug development, particularly on the oral iron chelator, one of the subsets of thalassemia or ...

Discuss the impact of chronic medical conditions on adolescents (12-18 years) and identify ways of promoting resilience or positive development.

Introduction
Many adolescents live out their daily life suffering from a chronic illness. This can be both physical and mental. Chronic illness can become an emotional burden on an adolescent’s life, which can lead to negative impacts on an individual’s psychosocial and cognitive development before they reach early adulthood. An adolescent is a person from the age of 12-18 years old. Chronic illnesses within an individual between 12-18 years old can have negative impact on the psychosocial wellbeing. This paper will analyze the social, psychological, psychosocial, and cognitive growth influences of chronic illness in adolescents.
Adolescents who ...