Abstract
The main Babesiosis diagnostic tests available are microbiological and serological. Unfortunately these tests have low specificity and sensitivity. Two molecular tests, the Polymerase chain reaction (PCR) and Fluorescent In-Situ Hybridization (FISH) tests, developed by IGeneX have great potential. Using 100 mice models the sensitivity and the specificity of the two tests will be determined and compared with the serological test.
1.0 Introduction
Babesiosis is a disease caused by an intracellular parasite, Babesia, which infects erythrocytes. Four main species of this parasite are known to infect humans; Babesia microti, B-MOI, B. divergens and B.duncani. Babesiosis is transmitted by ticks and has symptoms such ...