Medical compliance in schizophrenia is important for mental status and social position in the future. Also medical compliance is important for the timing of the psychotherapy and social rehabilitation activities. According to retrospective studies, schizophrenia correlates with less favorable outcome of the disease over a longer period for patient whom did not have prescribing medical therapy. Despite the fact that many patients achieved remission of symptoms, medical noncompliance adversely affect the patient's quality of life. The authors believe that the recovery criteria are important as the absence of acute symptoms and restoration of adequate social functioning. The patients with schizophrenia in remission have accompanying symptoms of anxiety, so it can be an effective use of antipsychotic drugs with sedative effects (this is recommended on the basis of good practice, based on the clinical experience of group leadership development). For patients with schizophrenia, antipsychotic drug choice can be determined by its potential impact on depressive symptoms.
In the appointment of antipsychotic medication should be provided with monitoring physical health. In the appointment of antipsychotic should be considered a therapeutic response in the past and side-effect profile of the drug. Patients with remission recommends using it antipsychotics, at least for several years. Antipsychotic agents associated with a wide range of side effects that may affect the condition of physical health. In two pragmatic trials of antipsychotic treatment marked their effectiveness during periods of average and long duration of the reception. In this paper, the main method of evaluation findings was the completion of treatment for any reason. In the systematic review authors found no studies on the transition from receiving one antipsychotic to another during initial treatment of the first episode of schizophrenia. Recommendations are based on the guidance of the conciliation guidance that an important predictor of treatment response and remission is an early improvement in the first two weeks, and a decision to change the treatment in patients with no therapeutic response can be taken for several weeks.
Many studies show that when choosing a maintenance treatment should take into account the preferences of the patient, the severity of the disease, the likelihood of compliance with taking the drugs, the therapeutic response in the past (Renton et al 1963;. Van Putten et al 1976;. Kelly et al 1987.). It is also necessary to consider the abuse of psychoactive substances, the presence of depression, worsening of cognitive functioning and side effect profile. Patients with schizophrenia is marked by continuing the use of antipsychotic medication, which results in reducing recidivism. For example “A significant percentage of outpatients, however, attribute noncompliance to forgetting” (Fenton et al., 1997, p.640). This effect can only apply to one or two-thirds of patients, and there is no safe methods cancellation antipsychotics for those patients who had the use of any benefit. Increased risk of recurrence associated with clinical factors such as the severity of the disease, lack of criticism, substance abuse, and poor adherence to taking medication.
Thus, patients with schizophrenia in the remission maintenance therapy appropriate to have antipsychotic agents. Generally, it must be a drug that is used during treatment of acute episodes of the latter, which means its effectiveness and tolerability. Although some patients experience relapse despite continued maintenance treatment, while others will only psychotic episode, regardless of compliance with maintenance therapy in the future. Some studies suggest that individuals with schizophrenia after the acute episode should adhere to maintenance treatment with antipsychotic agents for a period of two to five years. The medical compliance in schizophrenia has a great importance because it belongs to stressful events in life, so it implies the immediate environment of the patient, family reactions, friends, ways of thinking and behavior of the patient. Therefore, patients suffering from schizophrenia, a condition should be recommended remission maintenance therapy with antipsychotic drugs for at least two years.
References
Fenton, W. S., Blyler, C. R., & Heinssen, R. K. (1997). Determinants of medication compliance in schizophrenia: empirical and clinical findings. Schizophrenia bulletin, Vol. 23(4), 637-651.
