MicroRNAs are small, single-stranded, non-coding, 16–29 nucleotide RNA molecules comprising of an evolutionarily conserved class of endogenous ribo-regulators that regulate gene expression (Wiemer, 2007; Garzon et al., 2009). They were discovered in 1993 in the nematode Caenorhabditis elegans (Espinosa & Slack, 2006). Currently, 4167miRNAs are listed in the miRNA registry and 474 human miRNAs have been identified (Wiemer, 2007).
MicroRNAs are crucial for the development of vertebrates due to the fact that depletion of the components of the miRNA processing pathway, or interfering with maturation of miRNAs, is not compatible with life (Wiemer, 2007).
The miRNA ...
Reveal Literature Reviews Samples For Students
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Maurice Sendak's Where the Wild Things Are is considered to be a classic children's book that speaks to every child because of its drawings and simplicity in wording. The book tells of the story of Max, and his adventures in a jungle. It can be said that there are many different elements that make the book one that is wonderful and memorable. This is due to the depictions of the drawings that are coupled with the words, and the fact that it illicit memories of childhood for the individual reading it - whether they are an adult, or a ...
Introduction
Smith and Dawn realized that there has been an increasing trend in the development of social movements in the world. Citizens of a country, with the same agenda or grievances were coming together to develop movements into which they will use to air their views either in protests or insurgencies. Studies reveal that there has been the development of different kind of movements, for example gay, students and political movements (Swindler, n.d.). Due to the increasing trend in the formation of these movements, scientist and researchers have tried to come up with explanations on what are the main influences of ...
MicroRNAs are small, single-stranded, non-coding, 16–29 nucleotide RNA molecules (approximately 22 nucleotides in length) comprising of an evolutionarily conserved class of endogenous ribo-regulators that regulate (modulate) gene expression (Wiemer, 2007, p.1529; Zhang et al., 2006, p.9136; Garzon et al., 2009, p.168). They were discovered in 1993 in the nematode Caenorhabditis elegans (Espinosa & Slack, 2006, p.131). Currently, 4167 miRNAs are listed in the miRNA registry and 474 human miRNAs have been identified (Wiemer, 2007, p.1530).
The miRNA genes are dispersed across the genome in gene clusters or as single genes. At least 50% of the miRNA genes are ...
Exploring he theme of Isolation in Nathaniel Hawthorne’s short stories; “The Minister’s Black Veil”, “Young Goodman Brown” and “The Birthmark”
Nathaniel Hawthorne is the author of many short stories in which he portrays his characters with some dilemma where they must make up their minds about what is wrong from what is right. His stories end with morals that can be learned through his characters’ actions. Most of the stories he wrote are filled with themes of guilt and there are many themes of loneliness and sadness. His main characters are reclusive and lived sheltered lives. ...
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Classic English Literature
Hospitality has played a great role in the ancient Greek society, and this is highly evident in most of the classics written during those times. Homer’s Odyssey is a classic example of this fact. The Odyssey is one of the greatest masterpieces of Greek Literature. It is dated written between 750 and 650 B.C.E. (Notes, 1968) According to Fagles and Knox hospitality is understood to be a major part of the moral code. One of the most important factors that can be heavily noticed in this work of Homer is hospitality, with ...
Human body has complex physiological mechanisms that keep the vital functions in a well orchestrated manner. Depending on the needs of the body, a precise balance of essential internal communications, pathways or networks and secretions is maintained. A deviation from the normal state due to genetically, biochemical and environmental effects could negatively impact the integrated body machinery. In addition, the impact of age could also become additive in precipitating the ill effects. Age is the most important factor that determines the severity of a given condition. A precise management of such condition is possible only through appropriate investigations. The present description is ...
Gates points out a Harvard study stating the link between coffee consumption and suicide (Gates 16). The study concludes stating that coffee consumption on a daily basis lowers the suicide risk. The study was conducted with 200000 participants in total making a comparison between coffee drinkers and the non coffee drinkers in the case of suicide cases and found that about 50 percent of the risk involved in suicide is reduced as a result of drinking two to four cups of caffeinated coffee daily. The study also makes a comparison of caffeinated and non caffeinated beverages and identifies that coffee with caffeine are most ...
Introduction
Disease brings the abrupt end of Helmer’s marriage in the play ‘A Doll’s House’. The play has various characters. It has Mr. Helmer, Nora, Mrs. Linda, Dr. Rank and Krogstad as the main characters. The play contains three separate parts. In the first part, the stage conveys a positive and happy living home. Mr. Helmer’s marriage seems to be nice in the first part with limited challenges despite some hidden secrets emerging. It shows the Christmas joyous mood and buying of presents by Nina .
In the second part of the play, Mr. Helmer successfully secures the ...
The Seventh Day. The Theme of Ambitions and Failures
Yu Hua is one of the most famous and interesting contemporary Chinese writers. His books have been awarded numerous prizes and awards. His books are interesting primarily in the way that he shows life in modern China, and at the same time reveal Yu Hua as a master of the genre. Yu Hua acts as a supervisory watcher of modern Chinese life, and that's what draws the reader. His style is very original and recognizable, and the fact that the author is a supporter of realism makes readers to perceive ...
Introduction
The purpose of this paper is to show how the western media reported the Sino Japanese war and how China and Japan were portrayed. Several news reports portray the Chinese as being aggressive and violent individuals thus presenting the perception of the Chinese as being less victimized in the war. In contrast, the western media portrays the Japanese as being a rational and courteous group of people while their negative roles and atrocities in both world war II and Sino Japanese war have been overlooked. This paper will further identify the underlying reasons for ideological inclinations of wartime reporting. ...
Introduction
The fishing industry is a diverse industry that includes many activities and practices concerning fish and has been in existence for many decades. Nonetheless, the industry over the years has been faced with a wide range of issues with the most critical being environment issues. The environmental issues have thus resulted in the threat of aquatic life, particularly the fish family. The survival of lobsters particularly in Maines, New England in this regard has been forced to depend on water temperatures, the cleanliness of the of the habitat and the increasing concerns about the rising cases of the lobster ...
Divorce has a negative effect on children despite the parents’ best efforts of the parents to protect the emotional and social development of children during and after a divorce. The commonness of divorce in the society is a cause for concern in many educators and other members of the wider society. Children are often the ones who suffer most in divorces as they begin to feel as though their parents have forced them to make a choice that they should not have to make. The loss of the parent in the household can lead to educational challenges and social ...
Introduction
Recently, worldwide obesity prevalence has been raised rapidly and nearly doubled between 1980 and 2014, however in 2014 more than a half a billion of adult (18 years and older) were obese (11% men and 15% women) (WHO, 2014). Obesity and overweight are defined as excess body fat accumulation that leads to health risks and comorbidities. Adult weight can be classified based on the Body Mass Index. Hence, an individual having a BMI equal to or more than 25 is regarded as being overweight, while a person with a BMI equal to or more than 30 is considered obese ( ...
Achewood is one of the most important and critically-acclaimed internet comics of all times. He treats many important societal issues through anthropomorphic toys, including stuffed teddy bears. Specifically, in the ones that correspond to January 8th and 11th of 2006, the author Chris Onstad explores the social construction of masculinity and sexual relations. These interesting comics reveal masculinity as having to do with aggression sublimated by society, both through its norms and the market.
The first comic shows this through the invitation to “The Badass Games”. Different male characters receive a small letter that tells them to assist to ...
Introduction
There have been cases of corporate scandals in the recent past including the Enron, Tyco, WorldCom, and Global Crossing to name a few. These scandals fueled concerns regarding the financial reporting standards not only in the USA but also in economies where the financial markets tumbled as a consequence of the news of such scandals becoming public. These scandals arose because of weaknesses in internal controls and lack of independence by external auditors. For instance in the Enron, case, the external audit firm known as Arthur Andersen was criticized for lack of independence both in fact and appearance. The ...
Charlotte’s Web by E.B. White, Hana’s Suitcase by K. Levine, Why Me? By L. Allen and The Paper Bag Princess by R. Munsch present a wide range of conflicts and themes that are aimed at teaching children something about the world that surrounds them. All of the books are under the great influence of the ideology of the times they were written, so it is easy to spot different attitudes towards the same question, as for example, the classic emotional and empathic women in Charlotte’s Web and strong and brave Elizabeth in The Paper Bag Princess. ...
Horror through Imagination: How do Stephen King, Edgar Allan Poe, and Shirley Jackson create suspense in their stories “Harvey’s Dream,” “The Cask of Amontillado,” and “The Lottery”
Introduction
Suspense is a literary style that is adopted by most authors to invoke the creative minds of the audience. Therefore, the authors intentionally fail to draw a conclusion to an event in a story, but instead live it upon the audience to think. On the other hand, mystery is an occurrence that is beyond human understanding, and in most cases it is associated with murder. This essay is anchored on these ...
Law
THE LEGALIZATION OF MARIJUANA IN COLORADO
Introduction
The purpose of this study is to determine the effects of the legalization of marijuana in the state of Colorado by covering the following issues: 1.) the positive and negative effects of legalizing marijuana within the state; 2.) the effect of marijuana on public health and safety; 3.) the economic advantages after Amendment 64 was approved in the state of Colorado; 4.) the effect of decriminalizing marijuana to the police and law enforcement agencies. The outcome of the research will be an evaluation of the overall impact of the legalization of marijuana ...
Complete Name of the Professor
The Very Hungry Caterpillar
The Very Hungry Caterpillar is a children’s book written and illustrated by Eric Carle which was first published in 1969. The story was about a caterpillar who ate different kinds of fruits all throughout the week but remained hungry until he ate a leaf which made him feel better afterwards. Upon eating this much, the caterpillar noticed that he was no longer hungry nor was he little anymore—he had become a big fat caterpillar. He then wrapped himself around a cocoon for about two weeks and soon enough, he came out and became a beautiful butterfly.
First ...
Intercultural Friendship
Introduction
Scholars and academicians have paid little interest to intercultural friendships in spite of their obvious magnitude and regularity in the continuously expanding multicultural world. Intercultural friendships symbolize a close linkage between interpersonal and cultural dimensions of communication systems. The hardships involved in sorting them out might be one explanation why they attract so little interest from researchers. In recent times, it has become generally acknowledged that cultural diversity in the backgrounds of communicators contributes to differences in the patterns of communication behavior. This has made several researchers studying intercultural communication to make the assumption that it is a distinctive ...
The aim of this essay is to present you with the reflections drawn upon the readings of the novel ‘Passion’ written in 1987 by Jeanette Winterson. Jeanette Winterson has been widely acknowledged within the borders of the literary community as one of the writers who succeed in bonding their stories closely to mystery and passion, somewhere between magic and reality. This paper will present you with the main idea of Passion and will prove that people’s lives are conquered by Passion in such a way that Passion can neither be considered exclusively benefactoring nor destructive. It depends on the ...
Abstract
Studies in mechanics have evolved to be the most fundamental tool in the innovation of new materials and advanced technology. Specifically, studies in Continuum Mechanics, has been very influential in producing materials that exhibit various desirable characteristics at the expense of size and weight. Nanotubes are a perfect example of how this study has impacted the evolution in material technology. It has been used as the basis for the explanation of these complex materials as well as provisions for their behavioral effects during machining. The wide use of nanotubes in fragile fields like technical textile supplements, truly depict the stretchy ...
The aim of this essay is to present you with a review of chapters 22-24 of the book ‘The Scarlet Letter’. Barlow (2000) refers to this book as ‘The magnum opus’ of Nathaneal. (Barlow, 2000). ‘The Scarlet Letter’ is a story of love, adultery, betrayal, faith, belief and social criticism which was published in 1850 and holds a little bit of all these elements which can attribute to it the characterization of being a romantic novel.
The historical context of the novel’s plot is the social environment of the society living and developing in the area of Puritan Salem, in Massachusetts ...
Whose story would you tell? Around whose basic point-of-view would you build the screen play? How will you resolve the story?
I would choose to write the screen play from the point of view of the journalists who are conducting the sting operation. It would portray the various attempts of the media to establish a connection between the regulatory authorities and the drug dealers and through this point of view the film would expose the regulatory system of Ireland, that the Government and the Police’s involvement in such dealings. It would be similar to an investigation where the ...
Edgar Allan Poe is a prominent American writer, poet, editor and literary critic, whose works are popular with the readers all over the globe. The timeless themes of Poe’s stories and the struggles of his characters are indeed remain relevant nowadays. His cocktail of death, love and suffer is of an undying combination. His short stories and poems are sodden with darkness, agony, mystery and obsession of inevitable death, they thrill and excite. The Pit And The Pendulum, The Black Cat, The Murders in the Rue Morgue, The Fall Of The House of Usher are only a few of his ...
Human trafficking is one of the common acts of criminal in Central America that has been at center stage since 1990s. The increased attention for this trade has been driven by United State initiatives, such as the United Nations Protocol to Prevent, Suppress and Punish Trafficking in Persons. Depending on the local dynamics, study reveals that, the activity has got different manifestations across the entire region (NOVA 1). According to a publication by the UNODC “Global Patterns on Human Trafficking”, the Central American country states are the source, transit corridor and destination. They act as a destination for women and children ...
Introduction
Rural urban migration in search of greener pastures and better living conditions has led to the escalation of homelessness in major cities of Egypt. Children are the most affected considering their tender age and the fact that they cannot do most of the things for themselves. Most parents abandon their children as they realize the challenge of providing for their needs. Other parents perish in sickness, disease and accidents and hence leaving behind helpless children. With no one to take care of them, destitute children end up spending their lives in their streets with the hope that they will ...
Abstract
The first article majorly focuses on the factors that lead to the lengthening of the duration of the civil war between the government and the rebel protagonists. Many factors are taken into account. This paper is based on the religious and spiritual factors that influence the decision making of a legislator. It majorly emphasizes on the facts that the religious belief of the legislator, the religious credence of the citizens and the spiritual views of the board of the legislator mainly influence the decision making regarding the state. It also focuses on the transition towards democracy, its sustainability and importance ...
The play Ma Rainey’s contains several characters who wield power over the other, and their circumstances. Power in this instance is an individual who has go the ability to influence another person’s circumstances by their actions or inactions. A person who thus has this attribute in them, gains the advantage of soliciting their partner’s bidding at will by playing into their power over them. Power in a character is an important ingredient in the play as it helps run the plot and sequence of the play by creating both opportunities and conflicts for the progression. In understanding ...
Introduction
Safety is organizational requirement that helps in reducing risks to employees and customers. Organizations need to determine appropriate criteria that help in enhancing safety culture. Safety culture entails prioritization of safety measures within an organization through showing an obligation of security at different levels in the organization. Safety culture is part of the core values that all employees and customers should observe by performing their obligations. It incorporates characteristics and attitudes in an organization and individuals towards the creation of safety priorities and their significance. Safety initiatives are favourable with the existence of a workplace culture that reduces errors and ...
Introduction
Healthcare professionals have differed on the size of adequate nursing in hospitals. Research has clearly revealed that staffing of nurses has a direct effect on quality care. Quality care, on the other hand, influences patient satisfaction and recovery. Studies show that adequate nursing promotes quality care which in turn increases the rate of recovery in hospitals. Evidence-based practices reveal that as a result of low staffing levels, patient recovery has become poor with increased cases of shock and bleeding. The same evidence reports that patients recover at a faster rate when quality care is readily available due to proper staffing. Moreover, effective ...
ABSTRACT.
Poverty is in its own a culture and a socio-economic class, which traps individuals in a vicious cycle that are hard to break. Education plays a crucial role in breaking this cycle, but under normal circumstances achieving while faced with this calamity is a challenge. Teachers working with students from low economic backgrounds face the consequences of the culture of poverty, which goes to the extent of failing their state tests. Working with such students needs an understanding of poverty, and what they can do to address their literacy needs. This study provides a review on education achievements and poverty in order to examine the ...
PART A
Question 1
Atticus Finch, although belonging to the white community, defends Tom Robinson, a subjugated black who stands of raping a white woman. Through his actions, Finch promotes equality and liberty, having a simple purpose of having justice served, regardless of race. However, he is opposed by the accusers; Mayella and her father Bob Ewell, while other members of the white community term him a "nigger-lover".
In the novel, Bob Ewell is portrayed as a villain. His disregard for other human beings and his uncaring attitude towards his own family reveal that he is a man of limited values. It is his hatred ...
Hamlet’s Antic Disposition: Real or Unreal
The young prince Hamlet decided to put on an “antic disposition” to find out if the supposed ghost of his father had been telling the truth about its death. But as the play progresses, there are moments when Hamlet’s insanity seems to become less and less of a pretense and seems to become more and more genuine. Most of his actions and thoughts are consistent of that of an insane person; however, some of his actions and thoughts also indicate that he is aware of this and that it is all part of his act.
Insanity is a very broad ...
"Are Protein-Protein interactions likely to be valid therapeutic targets for cancer therapy?"
In her paper entitled “Protein-Protein interactions and cancer: small molecules going in for the kill” Michelle Arkin raises questions regarding the grooved and linear regions that permit protein-protein bonds, the binding peptides also found in those regions, if those interfaces are tractable for small molecule discovery and what compounds might serve as bonding agents. Further investigation of compounds would include if they are active, inhibiting, and do they help further characterize the target. She documents tubulin and several others that have potential. Her conclusion confirms that ...