Serum Reports Samples For Students

Based on the initial symptoms, the patient most likely suffers from hypothyroidism or low thyroid hormone disorder. Further clinical tests and an examination of the family’s medical history reveals that the particular disorder could be Hashimoto’s disease; also called Hashimoto thyroiditis. Hashimoto thyroiditis is classified as an autoimmune disease. In autoimmune disease, one's immune system attacks the body’s tissue specifically the thyroid gland (Skugor & Wilder, 2006, p.2). By attacking the thyroid gland, the disease reduces the gland’s ability to produce thyroid hormones of substantial quantity. This condition leads to hypothyroidism. Thyroid hormone deficiency presents with ...

Quantitative Article Critique

Methods, Results, Data Analysis and Findings
The quantitative research article chosen to be discussed was entitled Predictive Values of Semi-Quantitative Pro-Calcitonin Test and Common Biomarkers for the Clinical Outcomes of Community-Acquired Pneumonia. The respondent population was mainly composed of people who have been hospitalized as a result of having been diagnosed with Community Acquired Pneumonia between August 2010 and October 2012 using the semi-quantitative serum PCT Test. The objective of the research was to determine whether there is an existing relationship between the semi-quantitative serum pro-calcitonin (PCT) test (BRAHMS PCT-Q) and the clinical outcomes of patients with community acquired ...

Introduction

In any blood bank laboratory, definite tests must be done on all donated blood. This incorporates typing to verify the donor's ABO blood grouping and Rhesus factors in addition to several screens to guarantee the safety of the blood. Screening is usually conducted for unanticipated red blood cell antibodies that could cause severe reactions in the recipient and bacterial contamination in components of platelets as well as present and precedent transmissible infections. Each unit of donated blood is usually tested for Hepatitis C, HIV, Human T-Lymph tropic Virus, Syphilis, West Nile Virus and Malaria. But before any test is ...

Cell culture is an in-vitro technique of cultivating cells under controlled conditions and in sterile conditions. The technique was first developed by Ross Harrison in 1907. During the process of cell culture, the cells are detached from their tissue of origin and segregated from each other, either by mechanical or enzymatic means. The detached cells are then transferred before culturing them in cell culture plate or flask. The first generation of producing cell through this method is called primary cell culture. The cells from the primary culture are transferred to a new culture plate with a fresh medium to ...

Glade Bender JL, Lee A, Reid JM, Baruchel S, Roberts T, Voss SD, Wu B, Ahern CH, Ingle AM, Harris P, Weigel BJ, Blaney SM. Phase I pharmacokinetic and pharmacodynamic study of pazopanib in children with soft tissue sarcoma and other refractory solid tumors: a children's oncology group phase I consortium report. J Clin Oncol. 2013 Aug 20;31(24):3034-43.

This study describes a phase I clinical trial of “Pazopanib” in pediatric patients suffering from soft tissue sarcoma (STS). Pazonapib is an anti-angiogenic drug. It is a competitive inhibitor of ATP molecule1,2. It competes with the ‘substrate’ ...

of HT22 Cells derived from Mouse Hippocampus

Sections I and II

Biology
Section I
1. Introduction
Fluorescent protein development research has gained increased knowledge about the range in the color palette available from the Aequorea Victoria jellyfish. The wavelength emissions in the blue to yellow range are now better understood. [1] Another area that has seen a great improvement in knowledge is the understanding of emissions of the monomeric fluorescent protein emissions in the orange to far-red spectral region. [1] The spectral region of fluorescent in the orange to far-red is derived appropriate reef coral species. [1] This area of research ...

1. Which of the following is an antidote for benzodiazepine overdose or toxicity?a. Buspirone (BuSpar)b. Hydroxyzine (Visteril)c. Flumazenil (Romazicon)d. Naloxone (Narcan)There is one other drug overdose antidote in the above list. Name the drug and its mechanism of action. Flumazenil (Romazicon®) is another drug given to reverse the depressant effects of benzodiazepine and thus useful for overdose treatment. It acts as a competitive antagonist of benzodiazepines, having high affinity to GABAA receptors, which is the BZD binding site. This allows it to specifically target benzodiazepine and drugs with similar MOA such as zolpidem, but not other ...

Chemistry

Trizivir:
Ingredients: 3 synthetic nucleoside analogues with inhibitory activity against HIV-1. “A recently approved antiretroviral looks like a nucleoside reverse transcriptase inhibitor (NRTI), but it acts like a protease inhibitor” (Portyansky 1999).

Active Ingredients:

1. abacavir sulfate, 300 mg (aka Ziagen™)
2. lamivudine, 150 mg (aka EIVIR™ or 3TC™)
3. zidovudine, 300 mg (aka RETROVIR™ or azidothymidine, ZDV or AZT because of Azide functional group).

Additives:

1. titanium dioxide
2. hypromellose
3. yellow iron oxide

Coating on Tablets

Is FD&C Blue No. 2, hypromellose, polyethylene glycol, titanium dioxide and
yellow iron oxide

Inactive Ingredients:
1. sodium starch glycolate
...

Chemistry

2. The nano carrier needs to remain in suspension in H2O, PBS, human serum, etc. What type of polymer do you need to use to decorate the surface of the nanocarrier to achieve this goal?
In order to maintain the nanocarrier in suspension in water, Phosphate-Buffered Saline (PBS), human serum a suitable solution a polymer is needed on its surface. The polymer used needs to accomplish three goals. The polymer needs to decorate the nanocarrier surface to enhance suspension and secondly, to prevent protein absorption. Another characteristic is that the polymer evades the immune system. PLGA poly(lactic-co-)glycolic ...

Introduction

Initially there were beliefs that, MMPs are jointly able to degenerate all constituents making up the extracellular matrix (ECM) together with basement membrane that confines their operations to tissue reconstruction as well as the preservation. Nonetheless, the contemporary studies also signify that MMP-1 is responsible for controlling the production or else the activation of the chemokines. At this point, it is critical to understand that MMP-1 is among other MMPs.
Similarly, the knowledge holds it that MMP- 1 cleaves a peptide bond beforehand a residue comprising of a hydrophobic adjacent chain, for instance Met and Leu. The other sideways chains cleaved ...

Report Epidemiology Cardiovascular diseases and dietary fats

- Introduction
- Cardiovascular Diseases
- What is Cardiovascular Diseases (CVD)?
CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels such as coronary heart disease, atherosclerosis, hypertension, stroke, peripheral vascular disease and heart failure. Coronary heart disease (CHD) is the most deadly CVD that due to lacking blood flow to the network of blood vessels surrounding the heart, also named coronary artery disease (CAD) or ischemic heart disease (IHD) (Nabel and Braunwald, 2012).
- The pathology of heart attack and stroke
Atherosclerosis is the major cause ...

Lab report discussion and results

Introduction
The experiment is aimed at studying about the protein content in the cells and tissues of various organisms and the ways of regulating the growth of some tissues in the body of the animals like in our case we used the rabbit tissues in determining the feasibility of the experiment. The process begins with the ability to look at the process of obtaining the protein from the sample given and how to quantify the amount of protein in such cells.

Method:

Protein extraction
The process of protein extraction involves three major processes which must be followed in ...

Introduction:

In 1976, Marion Bradford designed the Bradford method that is widely used in measuring the concentration of protein in a solution. When Coomassie Blue is added to a solution containing protein, the solution colour changes from brown to blue and this is attributed to the formation of a protein complex. The concentration levels of protein can therefore be measured by observing the dye color, which fully absorbed at a certain wavelength. The standard curve is used to calculate the concentration of protein because it represents the known BSA (bovine serum albumin) dilution. (Harvard, 2012)
A study by Daiet (2008) analysed murinae in ...