- Heterogeneous nuclear ribonucleoproteins is a protein that comprises of RNA binding proteins. It is a complex made up of RNA & proteins that is characterized by binding of premRNA. This occurs in the nucleus during the transcription and post transcriptional stages of preMRNA. The protein has different roles which include; prevent formation of secondary structures by preventing folding of pre-mRNA, inhibit the interaction with other proteins, usually has a link with the splicing apparatus and transportation of the mRNA away from the nucleus. This type of protein is a multidomain protein with multiple RNA binding proteins. RNA recognition Motif which is the commonest ...
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Introduction
Genetic evolution refers to change(s) in inheritable traits occurring across succeeding generation of organisms. The change (evolution) is responsible for the diversity at all levels including the molecular level e.g. genetic variations, individual organisms in the same species (intra-species variations) and among species (interspecies variations). It is believed that all organisms emanated from common ancestry about 3.7 billion years ago and then evolved over time to the present biodiversity. Therefore all organisms have some shared traits at the morphological and molecular level with the species sharing a more recent ancestry having more similar traits. The process of evolution involves ...
Choose a gene that has been implicated in a human developmental disorder
FOXP2 is a gene that codes for a member of the transcription factors’ forkhead /winged-helix family, FOX. It is situated from base pair 114,086,309 to base pair 114,693,771 on the chromosome 7’s long (q) arm at position 31. The gene has 42 distinct introns, which include 41gt-ag and 1 other. The first FOXP2 report depicted 19 exons, of which two, namely 3a and 3b, are variably spliced into transcripts that cover about 300 kb on the chromosome 7q31 (Lai, Fisher and Hurst).
Several alternative transcripts, as well as protein isoforms, have been predicted on the ...
Abstract
Patients put immense trust in the healthcare providers, and in return expect safety in their hands. Healthcare Informatics, and electronic health records in particular goes a long way in ensuring their safety. The EHR improves care through safer, more accurate and complete information being shared among all the healthcare providers. Wait times for appointments - procedures, and access to community care facilities - are reduced. So are for the laboratory test results and clinical diagnosis. The electronic systems also ensure enhanced security of health information through encryption. It also allows doctors access to secured patients’ information. These include patient physicals, ...
Introduction
The healthcare system is undergoing a lot of changes in recent times. There are changing roles of the nurses in care and delivery of services. Nurses are more educated and advanced than the old times where their roles were limited to a narrow scope. There is a need for the nurses to deal with change in a positive way. It must be noted that each change comes with resistance from the workforce but the mangers must apply the best ways to overcome the resistance. There is a lot of changes in the nursing field including: online documentation, staff scheduling rotations, shift change, using arm ...