Click Chemistry describes the biocompatible reactions that are high yielding, that are very simple to perform, have wide scope, that need no chromatography to remove their byproducts and that can be conducted in easily removable solvents. The synthesis of first triazole was reported by Arthur Michael in 1893. In the 20th century, Huisgen discovered the catalyst of copper, 1,3-dipolar cycloaddition which required the temperature of 100 degree Celsius. This reaction of copper is a highly versatile reaction which does not require any specific reaction conditions and can easily be performed with various solvents, wide temperature range and pH, ...
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Introduction
The Anti-Markovnikov process in organic chemistry generally involves addition reaction method of an electrophilic substituent, HX to an alkene or alkyne compounds, in such a way that the Hydrogen atom in the HX electrophile are chemically bonded to the carbon atom containing the least amount of Hydrogen attached to it. This addition process commonly uses catalysts or additive compounds in order to hasten the reaction since the process is quite expensive and toxic in nature. Furthermore, there is also a limited number of reactions involved in using the Anti-Markovnikov addition, making its research more difficult to expand and develop.
Anti-Markovnikov Addition of Alkoxides to Alkynes
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