Essays on Antitrypsin

Transcriptional regulation of gene expression

Gene expression in eukaryotic cells is regulated at transcriptional, post transcriptional and translational levels (Tomizawa,  Lekstrom-Himes, and Xanthopoulos 17). Transcriptional control is the primary means of regulating gene expression. Eukaryotic transcriptional control functions at three levels: modulation of the activities of activators and repressors; variations in chromatin structure; and effect of activators and repressors on assembly of initiation complexes (Lodish et al. 368). Regulation of transcription initiation is the most widespread form of gene control in eukaryotes. However, in some cases, transcription may be attenuated and regulated at subsequent steps, such as during or after the transcription process (Cooper ...

Introduction

Malta has a publicly funded health care system similar to the one used in the United Kingdom with free health care at the point of delivery for all citizens and registered long term residents. Private health care co-exist along with the public system on a “pay as you use” basis and is mainly used by foreigners and contracted private physicians. The Maltese Ministry of Health is responsible for oversight and regulation purposes besides spear heading campaigns in the health sector. According to Murray & Frenk, Malta has the fifth best health care systems on the world beating developed countries such as the ...