Essays on Benedetti

Business Ethics and the Commercialization of Transplant Organs

Business Ethics and the Commercialization of Transplant Organs Currently, commercializing organs from either deceased or living donors can be prohibited legally in many parts around the world. The objective is to prevent commercialization of organs as well as ensuring a certain level of equity in gaining access to transplantation of organs. Moreover, certain proposals presented recently suggest that some forms of compensation (for instance, direct payment, tax credit, reimbursement, or moral’ incentives like honorary medals) can be permitted and explored. An issue that emerged recently, which provides considerable attention, is public solicitation of those organs received from deceased or ...

Von Gierke Disease

Introduction Von Gierke disease or Glycogen Storage Disease Type 1 (GSD-1) belongs to a group of rare metabolic disorders with a reported incidence of 1 case per 100,000 births per year. The clinical condition results from deficiency of key enzymes in the glycolytic pathway resulting in an increase in intermediate metabolites and accumulation of glycogen in the affected tissues. It is a genetic disorder with a natural history of severe developmental abnormalities and long term complications. This paper provides an overview of GSD-1 based on studies published in peer reviewed journals with a focus on its genetic determinants, clinical picture, available therapeutic ...