This stage starts with target identification. A biochemical mechanism established in a disease condition is chosen. Thomas (137) establishes that drug candidates, discovered in biotech/pharmaceutical research labs are tested for their contact with the drug target. Numerous molecules for all potential drug candidates undergo rigorous screening process. This may include functional proteomics and/or genomics among other screening methods. After confirming interaction with target drug, they classically validate that target through checking for activity versus disease condition that the drug in being developed. After vigilant review, one or several lead compounds are chosen. There is no specified duration of time for ...
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