Essays on Calcium Channel

DISCUSS THE ROLE OF ION CURRENTS IN DETERMINING THE SHAPE AND DURATION OF CARDIAC ACTION POTENTIAL

Introduction Selective permeability to various ions is an important characteristic of cell membranes, one that determines myriad cellular functions. In animal cells, ion permeability and the electrical potential generated thereof determines the activity of neurons, myocytes and the like. The electrical potential depends on the concentration of the ions inside and outside any given cell, the permeability of the cell membrane to the ions and the ion channels that are present on the surface of the cell. Cardiac cells also possess different ion channels on their surface. These determine the two types of electrical potentials, namely, resting membrane ...

Introduction

The aim of this paper is to present a comprehensive report on a case study conducted on an individual who is displaying symptoms of hypertension. The paper explicitly explores as a chronic disease and some of the aspects that will be touched on include its epidemiology, Pathophysiology, differential diagnosis, treatment plan, drug analysis and follow up care.

Hypertension, also commonly referred to as high blood pressure is a body condition in which blood vessels, specifically the arteries high and persistent pressure. This high pressure makes it hard for the heart to pump blood to all the other parts of the body. Hypertension inadvertently ...

The regulation of blood pressure and fluid homeostasis in the body occurs thorough an endocrine pathway called the renin angiotensin (RAS) pathway. This is a multistep pathway in which two step conversion of angiotensinogen to angiotensin I by rennin and subsequent conversion of angiotensin I to angiotensin II by angiotensin converting enzyme (ACE) occurs (Fig 1a). The RAS involves a number of peptides, receptors and enzymes partake in this highly regulated system. The angiotensin II, however, is the key biological player of this pathway. Uncontrolled activation and improper regulation of the RAS pathway leads to hypertension, organ failure and eventually death. ...

Introduction

The aim of this paper is to present a comprehensive report on a case study conducted on an individual who is displaying symptoms of hypertension. The paper explicitly explores as a chronic disease and some of the aspects that will be touched on include its epidemiology, Pathophysiology, differential diagnosis, treatment plan, drug analysis and follow up care. Hypertension, also commonly referred to as high blood pressure is a body condition in which blood vessels, specifically the arteries high and persistent pressure. This high pressure makes it hard for the heart to pump blood to all the other parts of the body. Hypertension ...