- Summary After a heart attack, the restoration of the cardiac function depends on the ability of the heart to generate cardiomyocytes, or new muscle cells. The ability is, however, weak and wanes with age. The alternative strategy involves delivering the newly grown cardiomyocytes to the damaged heart tissue. It requires the use of either induced pluripotent stem (iPS) or the embryonic stem (ES) cells. Embryos are the only sources of ES cells. On the other hand, the in vitro reprogramming of adult differentiated cells transforms them into undifferentiated stem cells. The method allows the production of iPS cells ...
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