Abstract
The primary aim of anticancer therapies is to induce the death of tumor cells. Cisplatin has done a good job in achieving this aim, which explains why it is the most commonly used adjuvant therapy of cancers. However, the success of applying CDDP and any other platinum compounds for cancer chemotherapy depends enormously on the ability to manage its side effects. This paper reviews the studies and literatures on cisplatin and some other similar platinum compounds. It presents its history and background, chemistry, mechanism of activity, as well as the side effects.
Introduction
The cisplatin has been described as a tiny little ...