Chapter I: Introduction
In the United States, Prostate cancer (PCa) is the most common non-cutaneous malignancy after lung cancer in men with an incident of 126 per 100,000 people. The American Cancer Society (ACS) reported that the number of new cases of men diagnosed with PCa by 2016 will be an approximately 180,890 cases. PCa is still considered as the second leading cause of cancer death in men. Also, the ACS added that the estimation for death will occur from PCa is 26,120 deaths in 2016. Today, many studies stated that mortality rate is gradually decreasing compared with the ...