Cruetzfeldt Jacob Syndrome (CJD) is a fatal disease affecting humans and is caused by infectious proteins called prions. It belongs to transmissible spongiform encephalomyelitis group of diseases. The disease occurs from the accumulation of prions PrSc that damages the brain cells. CJD can occur in a hereditary form or as an acquired form. The hereditary form results from a dominant mutation affecting prion protein gene (PrP). CJD is a communicable disease. Acquired infection occurs through iatrogenic transmission from hospital. Contaminated instruments used in surgery’s are an important cause for transmission in iatrogenic infection. The disease can also be ...
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