Qualitative research is relatively new to nursing research. Despite its being usually underused and undervalued, qualitative research is increasingly contributing to nursing knowledge (Hall, 2006). The purpose of this paper is to compare qualitative and quantitative research in order to examine their differences. The comparison will be done by examining an article using the qualitative method and two articles using the quantitative method. All articles are on the same topic, cystic fibrosis. All articles were published in well-known and reputable journals. The qualitative article is by Carpenter and Narsavage (2004) and the quantitative ones are by De Bias, et ...
Essays on Cystic Fibrosis
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Part 1
Cystic fibrosis is a disorder that has been proven to have profound effects on the genetic makeup of an individual. This condition mainly affects the lungs and the alimentary canal. The other body organs likely to get affected by the disease include the kidneys, pancreas, intestines and the liver. It has been established that the condition compromises the functioning of the body cells responsible for the production of digestive, mucus and sweat juices (Mayo Clinic., 2016). Under normal circumstances, these cells are usually thin and slippery but if they become affected, the secretions they produce turn sticky and thick. ...
The purpose of this paper is to review the etiology, pathophysiology, clinical manifestations, inheritance patterns, and recent advances in disease management of cystic fibrosis. Cystic fibrosis is a progressive and lethal disease resulting from an autosomal recessive gene (Singh, Rebordosa, Bernholz, & Sharma, 2015). The major problem associated with cystic fibrosis is the repeated lung infections that over time severely damage the lungs, scar and widen the passageways and limit the ability to breathe (Cystic Fibrosis Foundation, n.d.). As of 2013, there are an estimated 70,000 cystic fibrosis patients globally with 33,000 of them in the United States ( ...
Cystic fibrosis is a chronic, progressive and often deadly genetic disease that affects the body’s mucous glands. It follows that cystic fibrosis (CF) is evident in the body’s digestive and respiratory systems, particularly in children and young adults (Flume et al., 2007). In some cases, it affects the reproductive system and the sweat glands. A CF-like disease has been known over the past two centuries, but it was in 1938 that the term cystic fibrosis was first used. CF may also be considered to be an autosomal-recessive disease. Its estimated heterozygote occurrence is one for every twenty ...
Introduction
Cystic Fibrosis (CF) is the most prevalent genetic disorder in the Caucasian population, with an incidence of 1 in 2500 births. CF is a disease that affects many organs including the upper and lower respiratory tracts, pancreas, intestines and reproductive system. Over the past 20 years, our understanding of the manifestation and management of the disease has progressed dramatically. CF was once considered a condition of childhood and there was very little expectation that children would enter adult life. However, CF has become a multisystem adult disease with the increased survival attributable to advancements in standardized treatment, introduction of ...
Abstract
In a social-norm breaking situation, an audience member at a charity event for sufferers of Cystic Fibrosis and their families expresses an unpopular opinion. Cystic Fibrosis, or CF, is an inherited disease that is generally passed down from recessive carriers (who don’t have the disease themselves) to their children. It affects the secretory glands, causing mucus to build up in the various parts of the body. The condition causes early death in most sufferers, and the average life expectancy of people with CF is less than forty years (“What is Cystic Fibrosis?” 2013). The norm-breaker’s opinion does ...
(6 points) Compare and contrast mitosis and meiosis (include at least 3 comparisons and 3 differences).
Both mitosis and meiosis are usually associated the cytokinesis In both processes, end result is usually production of daughter cells from the parent cell The fundamentals in both processes are the same in that there is breakdown of nuclear membrane, genetic material separation into two groups, cell division and eventually the nuclear membrane in the cells reform
Differences
In meiosis, there are two rounds involved in genetic separation while in mitosis there is only one round. In meiosis, there is separation of homologous chromosomes ...
In days gone by if a woman gave birth to a daughter and not a son, she was considered at fault. If a family needed an heir to be a man-child and the mother didn’t produce one, she could well have been trouble. Now we know that in fact, the father contributes either the X or the Y chromosome determining the gender of the child.
In today’s world, when gender is not an issue, if the child is born with a disability are the parents to blame? It all depends on what kind of disability. There are some congenital conditions such as Down’ ...
Question 1: The main and supporting claims presented within the essay
The article talks about the importance of technology on the current medical field. Moreover, the article talks more about the importance of adoption of technology in the hospitals and other medical facilities so as to enhance improved results. The technology is important due to the fact that it is capable of detecting the causes to a disease before it occurs in an individual. The article therefore shows the audience the change that modern technology has brought to the society at large. The case illustrated shows the difference between the current modes of treatment and the older modes. The importance ...
Biology of Disease
Mode of action of;- Dexamethasone The Glucocorticoid receptors are discovered intracellularly in all tissues. They enter cells through inactive dispersion and structure a complex with a receptor protein (Rhodes & Hartnoll, 2002, P.10). This intricate then experiences an irreversible enactment and enters the cell core, where it ties to the DNA, hence prompting organic impacts instigated by these hormones, which include expanded hepatic gluconeogenesis, as well as expanded lipolysis (Ahmed, 2007, P.13). Dexamethasone is utilized to treat numerous provocative and immune system conditions, for example, rheumatoid joint pain and bronchospasm. Idiopathic thrombocytopenic purpura, an abatement in quantities of ...
Exercise 1: Anatomy of the Respiratory System
What are the two functions of the larynx? Larynx is a cartilaginous and a muscular structure while holds vocal cords together. It is used by human beings to talk, swallow and breathe. It is lined by the mucous membrane hence forming part of the respiratory system. Larynx protects the airways by closing quickly after mechanical simulation hence stopping respiratory and curbing the entry of foreign substances into the airways. The larynx also produces sound, controls ventilation and acts as a sensory organ.
Where does gas exchange take place in the lungs?
Gaseous exchange occurs in the lungs and for it to take place; there is the need for a place where ...
Cystic fibrosis
Cystic fibrosis is a disease relating to the exocrine gland function. It involves multiple organ system as a whole, but there are some specific organ dysfunctions caused by this condition. These are the chronic respiratory infections, and pancreatic enzyme insufficiency. There are also some forms of complications that are usually associated with the untreated patients. Pulmonary issues or involvement is found in 90 percent of patients surviving the neonatal period. It has been noted in recent times that the major cause of death relating to the cystic fibrosis is the end-stage lung disease associated with it. In the affected individuals, ...
My thesis statement is that medical charities are utmost important for the nation as well as humanity in general as they help to cope with medical emergencies and necessities thus saving several precious lives and providing much needed medical help on time. This is the reason I have chosen medical charities from among the other charities to donate the sum of $10,000 at my disposal. For efficiently gauging which are the best medical charities, I have done some preliminary research by poring through their websites in detail supported by secondary research of going through their performance parameters and ...
Abstract
Cystic fibrosis is an autosomal recessive genetic problem with major infections to lungs, pancres, intestine and liver. The main characteristic of the disease is abnormal transport of chloride, and sodium in the epithelium leading to thick secretions. It usually results from mutation in the gene for a protein known as cystic fibrosis trans-membrane conductance regulator (CFTR). This is a hormone which is usually involved in various body excretion processes. The main method of transmission of the disease is through genes. However, research has proved that it can be still transferred among people with no DNA connection The disease is ...
Cystic Fibrosis is a genetic disease characterized by the buildup of sticky and thick mucus inside the body that can potentially damage the organs (US NLM, 2012). The two most common signs of Cystic Fibrosis are damaged respiratory system and chronic digestive problems. The severity varies among the affected individuals. The disease is most common among Caucasian people (1 in every 2,500 newborns) and most rare among the Asians (1 in every 31,000 newborns) (US NLM, 2012). Cystic Fibrosis produces thick mucus that can block the airways in the lungs, leading to bacterial infection and severe breathing ...
Introduction
Cystic fibrosis is an autosomal recessive condition that is caused by the mutation of the cystic fibrosis trans-membrane conductance regulator. The mutation affects the absorption of chloride ions which impairs the movement of sodium and water at the cellular level. This results in production of abnormally thick secretions that cause inflammation and damage to the cell. This affects the functioning of the organs. It is one of the most common genetic disorders that affects Europeans. Statistics indicating that one out of 2381 people in the United Kingdom suffer from the condition. The complexity of the disease calls for a ...
Research Paper
Research paper
The article “One breath at a time: living with cystic fibrosis” presents a qualitative investigation to describe the living experiences of families caring for a patient of cystic fibrosis (CF). Several quantitative, ethnographic and grounded theory studies have been done involving the patients of CF and their families. These studies aimed at research on stressors and interventions for CF and are valuable in understanding coping in families lived with (or living with) CF for extended periods of time. However, these studies do not explain the experience of living with a family member with CF. The objective of this research was ...
Research shows that around 30, 000 Americans have Cystic Fibrosis with over 1000 new cases diagnosed every year. Analysts suggest that it occurs evenly to both the females and males and affects generally every race. This condition is more common among the white babies. One in every 3,200 live white births in comparison to one in every 3,900 live births amongst all Americans appear to be suffering from the condition. At the age of three, most patients are diagnosed and only ten percent of the most recent cases are usually by age eighteen and above (Children’s ...
Introduction
Human Engineering is an applied science that coordinates the design of systems, devices and the working conditions with the requirements and capacities of workers. It can also mean the alteration of human body cells in order to fight genetic and chronic diseases or to improve human intelligence, appearance, memory or some other desirable traits (Baylis & Jason, 24). In this context, human engineering is viewed from the context of genetic modifications of human cells. Genetists who conduct scientific research into human engineering and sports owners advocate for it while purists who advocate for the maintenance of the human species from ...
Question 1: Explain the pathophysiologic defect of Cystic Fibrosis.
A mutation of a single gene, on chromosome 7, leads to the disease, cystic fibrosis. The gene is responsible for encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The normal CFTR is a regulator of chloride channels, which can lead to the regulation of chloride and sodium channels on the surface of the cell. The most common mutation leading to an abnormal CFTR is a mutation is delta F508. The disease can have different phenotypic manifestations depending on the extent of the mutation. The differences in chloride transduction leads to abnormal secretions in various organs, such as the lungs leading to ...
#1 MAKE OBSERVATIONS Some genetic diseases are very common in people with certain heritages. Examples include sickle cell anemia in persons from African descent, Tays Sachs in Jews from Germany or Eastern Europe, and cystic fibrosis in Caucasians. #2 ASK QUESTIONS
Is there a way to narrow down genetic issues specific to certain heritages?
#3 HYPOTHESIS There are factors within a person’s genetic code (DNA) and factors within the way persons of a certain heritage live that concentrate genetic issues within a particular heritage. #4 PREDICTION Genetic issues will be the result of changes within the affected individual’s DNA that mean they have differences in the way their ...
INTRODUCTION
The human body consists of tissues and organs that contain over 200 different cell types.1 these cells carry out all the functions required for viability and reproduction. It was argued long ago, that in some tissues, the differentiated cells have a shorter life span and that they are not able to self -renew.2 This led to the notion that such tissues are maintained by cells that have an extensive renewal capacity, and the ability to differentiate and generate daughter cells. These cells were termed as ‘stem cells”.2 Stem cells generate only the differentiated lineages of the tissues they reside in, ...
Genetic testing also known as DNA based test, involves direct examination of DNA molecules to test for genetic disorders and diseases (Gene testing, 2010). According to the Human Genome Project Information (2010), Genetic testing can be used for various reasons to include: - Identifying people who carry one copy of genes causing diseases such as Huntington’s disease. - Pre-symptomatic testing of adult onset diseases/disorders such as Huntington’s disease - Forensic testing and determining paternity. - Newborn screening and pre- natal testing. DNA stands for Deoxyribonucleic acid, and these are chemical Data bases ...
Dear Grandma,
Our body has tissues and organs that are made up of different types of cells. Each cell contains the deoxyribonucleic acid also known as DNA. This double-stranded DNA is made up of 4 chemical molecules also known as bases: adenine (A), guanine (G), cytosine (C) and thymine (T). In the DNA, A always pairs with T; C always pairs with G. These strands are nothing but sequences of these bases that run really long. So typically a short sequence of DNA if written down in English will read:
AGTCCCGGTTC
TCAGGCCAAG The DNA sequences are 99% alike in all humans, but ...
Vitamins are essential organic nutrients required in minute amounts for the body's optimal functioning. They could be water soluble or fat soluble. Water soluble vitamins include; vitamins Band C, while the fat soluble vitamins are; Vitamins A, D,E,K. Vitamin A was the first fat soluble Vitamin to be discovered in 1913.
Vitamin A's structure is depicted to the right. Retinol is the precursor of of retinal and retinoic acid. Both are active metabolites of retinol. Retinal plays an important role in vision while retinoic acid is the intracellular messenger which affects the transcription of some gene( Bates ...
Nurse Responsibilities
A nurse is a medical professional who focuses on taking care of sick individuals so that they can return to or improve their optimal health status (Philip, 2003). Unlike other medical professionals, a nurse has a lot of responsibilities. Some of a nurse’s main responsibilities include promotion of health, reducing the risks of a disease or treatment, and control of the spread of a disease. Sure there are a lot more responsibilities that a nurse has to fulfill (it may even vary from country to country) but this paper will only focus on these three.
Health Promotion
Nurses are considered members of the primary healthcare team. Primary healthcare ...
Cystic fibrosis
Introduction
Cystic fibrosis is a chronic illness that affects children. This medical disorder is also known as Mucoviscidosis and it is an inherited disorder, which is autosomal and recessive in nature. It affects two major systems (respiratory and digestive systems) in the children. Recent evidence has shown that disorders affecting the lungs are one of the highest causes of increase morbidity and mortality rates in the children (Pizzignacco & Lima, 2006). Associated complications are the major issues in cystic fibrosis. Technology and advancement in health care system has helped in reducing the associated mortality and morbidity because the disorder can now ...
Part I
Original DNA Strand:
3’-TACCCTTTAGTAGCCACT-5’
Transcription (base sequence of RNA):
5’-UTGGGUUUTCUTCGGTGU-3’
Translation (amino acid sequence):
3’-TACCCTTTAGTAGCCACT-5’
What is the significance of the first and last codons?
Explanation: The first and last codons are very essential in that they dictate and command the direction of the transcription and synthesis of mRNA from the 5’ end towards the 3’ ends. Additionally, the first and last codons act like terminal points where protein synthesis begins and where it actually ends hence these codons actually determine the size of the animo acids produced which determine the type of and size of protein synthesized (Hartl, 2011).
What meaning do these codons have for protein synthesis?
Explanation: These codons are ...