1. Biot’s respiration named after Camille Biot is an abnormal ataxic breathing pattern, where rapid series of shallow respiration are followed by a period of apnea. In order to known how AMP kinase, knock down leads to Biot respiration in mice; it is necessary to known how AMP kinase affects respiratory rate. AMP kinase is a metabolic sensor and is activated in response to stretching of the lung alveolar cells and other stressors. During respiration, the lung goes through cycles of expansion and contraction (Budinger et al., 2008). When the alveolar cells stretch during expansion, the 5′ AMP-activated ...
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Multiple sclerosis is an autoimmune disorder, which affects the central nervous system. It was first described as a separate disease in 1868 by Jean-Martin Charcot (Compston and Coles, 2008). The average prevalence of the disease globally is 30 people from 100000 (Milo and Kahana, 2010). However, the incidence of multiple sclerosis varies greatly depending geography. While in the African countries it happens comparatively rarely, its frequency is increasing consistently in Asia and America. In Europe, multiple sclerosis happens with the highest rate in the world. There are four clinical forms of multiple sclerosis (Compston and Coles, 2008). Relapsing-remitting MS ...
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