Introduction
Studies have shown that fescue toxicosis is caused by low levels of ergot alkaloids which are highly toxic in endophyte-infected tall fescue grass. It is believed that a number of the ergot alkaloids are involved in the modulation of physiological mechanisms in animals and man. One of the best approaches that can be used to solve the problem of fescue toxicosis from the body system is by adopting the process used by animals to remove the ergot alkaloids toxins from circulation. This can be achieved through understanding of the role played by the cytochrome P450 (CYP3A4) in the elimination of ...
