Hansch Analysis
Hansch analysis is used widely in the field of medicinal chemistry. It is the analysis that investigates the quantitative relationship and correlation between the compound’s biological activities with their physicochemical substituents. The global parameters considered in this method include the electronic, steric, hydrophobic, and other effects that use multiple correlation methodology (IUPAC). Application of the Hansch analysis includes the Quantitative Structure-Activity Relationship (QSAR). This application develops correlations between activity of the ligands and their properties. As a rule of the thumb, the Hansch model “gives information about the number of parameters to be selected for regression analysis in ...
