Suboxone is a combination drug, administered sublingually, of buprenorphine HCL and naloxone HCl dehydrate in a ratio of 4:1, used for the treatment of opioid addiction, for example in heroin addicts and narcotic painkiller abuse, in higher doses; and in lower doses is used for the treatment of acute and chronic pain (FDA, 2010). Buprenorphine is a μ receptor partial agonist and a κ receptor antagonist; naloxone is an opioid receptor antagonist, which has a higher affinity for μ receptors then full agonists do and can thus displace the full agonist from the receptor reversing the effects of opiate overdose, such as respiratory and ...
Essays on Drug Seizures
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