Introduction
Capsular polysaccharides are of high molecular mass and low molecular weight cell-surface polysaccharides of Gram-positive and Gram-negative bacteria (Wang et al. 2000). They facilitate evading the immune system; therefore, the production and extraction of this layer is a prospective therapeutic target (rcsb.org). In the Gram-positive bacterium Streptococcus pneumoniae, strain TIGR4 the Cps4B is tyrosine protein phosphatase CpsB. The phosphatases have capability to dephosphorylate their analogous autokinases, instead of their similar functionality equivalence; they don’t demonstrate sequence homology. This capsule or CPS act as an interface border between a microbe and its environment that presents an expansive biological and clinical significance. ...