Rheumatoid Arthritis, which is the most common type of chronic inflammatory arthritis, can affect any organ system. What causes Rheumatoid Arthritis is still unknown. Genetic susceptibility combined with an external trigger, such as infection, smoking, and trauma, is theorized to cause the disease expression. It is believed that these external triggers cause an autoimmune reaction, resulting in chronic joint inflammation and synovial hypertrophy along with other manifestations (Hammer and McPhee, 2014). It has been observed that the patients of Rheumatoid Arthritis have higher levels of the Epstein-Barr virus (EBV) antibody titers and virus-infected B cells than the general people. ...
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