Cortisol is a steroid hormone synthesized in adrenal glands with a myriad of functions mainly in the endocrine and immune systems, and produced during stress circumstances. Under normal conditions, stimuli such as a pathogen release immune proteins called interleukins, which further activate T-lymphocyte cells. T-cells multiply to amplify the immune response and ultimately attack the pathogen (Abbas, 2014). Other immune responses are simultaneously activated, e.g. the complement system. The complement system exerts its functions through three pathways: classical, alternative or lectin pathways. The main activators of the classical pathway are antigen-antibody complexes, which trigger a series of events mainly mediated by complement proteins ...
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Abstract
User adaptive system is everyday becoming an important activities, as users are always expecting intellectual services from them. What everyone should know and understand on the user adaptive system is the user model. Old devices, which are still learning how to create this user model, are mostly too rigid to understand the uncertainty of different people. Computing methods can be easily used to handle and even process human uncertainty as well as stimulating human decision-making. This context explains how soft computing methods, including neural networks, fuzzy clustering, fuzzy logic and genetic algorithms can be used. For different techniques, applications, ...
Introduction:
The function of many living organisms is coupled with a vast array of cells .These units in turn serve as role playing agents for the fundamental physiology that determines the well being of organisms. However, variations in cellular environment are thought to regulate cell growth, division and survival. A network of molecular pathways or signaling events are interlinked with the cellular functions .Alterations in this specific functional aspect could lead to unnecessary complications which may lead to health abnormalities. In such context , the present description is concerned with highlighting about mTOR Signaling in Carcinogenesis. mTOR stands for mammalian target ...
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ORDER AN ESSAYThe G- protein coupled receptors (GPCRs) include a group of receptors that still undergoes intense research. Such research occurs at both academic levels and in the pharmaceutical industry. Several advancements occurred recently in the structure of the G- protein coupled receptors. There appeared new crystal structures as well as ground states and active states. Such advancements in the structure of these proteins helped in the further understanding of the receptors especially in the therapeutic fields. It also possesses an immense impact on the GPCR field (Andrew, 2008, pp.6). Several fundamental factors help in the understanding of these receptors. Such ...
