Electrophilic Aromatic Substitution to yield 4-Bromoacetanilide
Introduction Halogenation is a common process in organic synthesis. It is used in industrial and research synthesis as halogenated compounds are used for numerous widely used goods, including plastics. The lab aimed to perform monohalogenation of acetanilide. The reaction is specific since it is performed without catalyst. The typical halogenation is realized in presence of Lewis acid. Halogens molecules are electrophilic, and do not actively react. In presence of Lewis acid, the interaction is rather active.2 The lab used catalyst-free halogenation. The acetanilide molecule contains the acylated amine. As a result, the electronic density is shifted towards the amine ...
