1. Introduction Opioids such as codeine and morphine, are the active pharmaceutical ingredients of many drugs such as pain relievers (analgesics), cough suppressants, sedatives, etc. Opioids are derivatives of opium and bind to the μ-opioid receptor (μOR). The coupling of the μOR to Gi, the inhibitory subunit of the G-protein, blocks the activation of adenylyl cyclase and results in the analgesic effect. The opioid receptors belong to the G protein-coupled receptors (GPCRs) superfamily and specifically to the rhodopsin-like family A. These receptors consist of two closely related members, namely, δOR and κOR (Manglik et al. 2012, p. 322). ...
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The Themes Addressed on Bastard of the Party and their Relation to the Rest of the Work Engaged in the Entire Program
The concept of war as an ultimate resolution in the documentary Bastards of the party has been highlighted prominently. This has been reflected on regard to the approaches considered by the listed gangs towards the address of their social disparities. The concept of war being deployed in the settling of such disputes extends further to the involvement of security forces. Their approaches, as elucidated in addressing the gang wars, seems to be advised from the same concept ...
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