Full title- A COMPARISON OF THE INHIBITORY EFFECTS OF METAL IONS
Enzymes are an essential part for the functioning of the human system. Most of the enzymes require binding of metal ions and other non-protein components for their appropriate functioning. Such non proteins, which facilitate the functioning of enzymes, are called cofactors. The cofactors can be an organic cofactor as Thymine Pyrophosphate (TPP), Flavin Adenine Dinucleotide (FAD), Nicotinamide Adenine dinucleotide (NAD); or inorganic cofactors like metal ions, Mg2+, Cu2+, Mn2+, Zn2+ and Iron-sulphur clusters. When the enzyme is bound to a cofactor, ready to carry out its function, it is known as a ‘Holoenzyme.' An enzyme without a ...