The purpose of this paper is to review the etiology, pathophysiology, clinical manifestations, inheritance patterns, and recent advances in disease management of cystic fibrosis. Cystic fibrosis is a progressive and lethal disease resulting from an autosomal recessive gene (Singh, Rebordosa, Bernholz, & Sharma, 2015). The major problem associated with cystic fibrosis is the repeated lung infections that over time severely damage the lungs, scar and widen the passageways and limit the ability to breathe (Cystic Fibrosis Foundation, n.d.). As of 2013, there are an estimated 70,000 cystic fibrosis patients globally with 33,000 of them in the United States ( ...
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Abstract
Risk management is undertaken differently in varied sectors. In a survey of 415 projects in Brazil, the revelation came out that hiring a risk manager or planning for risk enhances project success rate. However, risk means diverse things for different sectors. In IT, some risks are desirable, because they disrupt the status, making some people redundant and increasing the opportunities for the skilled. Hence, the path taken to manage risk in the IT field is different from how risk is managed in other areas. The construction industry is intensive in the use of resources, and risk management should be ...