Mechanical ventilation (MV) causes oxidative stress that is responsible for adverse consequences on organs. In a situation of MV, the excessive pressure impairs the function of the mitochondrial respiratory chain leading to oxidative and nitrosative stress (Kavazis, 2009; Hafner et al., 2014). MV is commonly associated with hyperoxia where an excess of oxygen is provided. In such a case an oxidative stress can be induced when the oxygen pressure in the alveolar exceeds that of the normal breathing conditions because the biological system is not able to readily detoxify the environment from components such as reactive oxygen species (ROS) ( ...
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