1. Biot’s respiration named after Camille Biot is an abnormal ataxic breathing pattern, where rapid series of shallow respiration are followed by a period of apnea. In order to known how AMP kinase, knock down leads to Biot respiration in mice; it is necessary to known how AMP kinase affects respiratory rate. AMP kinase is a metabolic sensor and is activated in response to stretching of the lung alveolar cells and other stressors. During respiration, the lung goes through cycles of expansion and contraction (Budinger et al., 2008). When the alveolar cells stretch during expansion, the 5′ AMP-activated ...
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Describe the underlying pathology of COPD and the common pathological characteristics of the condition. Discuss the impact these pathological changes have on normal function, including how alveolar ventilation might be different in Mr Wenham compared to a normal individual. The hallmark pathological attributes of chronic obstructive pulmonary disease (COPD) are one, poorly reversible airflow obstruction and two, a progressive atypical inflammatory response within the lungs. The abnormal inflammatory response denotes the responses of the innate and adaptive immune systems to long-standing exposure to noxious gases and particles especially cigarette smoke. Notably, all cigarette smokers have some degree of inflammation ...
Facioscapulohumeral muscular dystrophy (FSHD) is a disorder in the muscle which is hereditary, and is defined by the weakness of the muscles on the face, scapula stabilizers, and the foot’s dorsiflexors (Lemars et al.). Muscular dystrophy refers to the degeneration of the muscle which advances over time and can be observed through the atrophy of muscles and an observed growing weakeness of the muscles (MDA). Early signs of the disorder exhibit the weakening and atrophy of the muscles in the eyes and the mouth area, in the shoulders, muscles in the upper arms, as well as the lower ...
Chronic obstruction pulmonary disorders and treatment options
Chronic Obstruction Disorder disease (COPD) is one the most prevalent cause of morbidity across the globe. It is a curable and partially reversible problem which is manifested by an obstruction in air flow and impaired health status. The patients who have frequent attacks of COPD have worst condition along with acute episodes of symptom exacerbation. The objective of the treatment is to avoid the symptoms through controlling it by including the lung functioning and health status. COPD is linked with abnormal inflammatory response of the lungs to noxious gases or particles. Patients below the age of 35 are at ...