Extended Methamphetamine Self-Administration in Rats Results in a Selective Reduction of Dopamine Transporter Levels in the Prefrontal Cortex and Dorsal Striatum Not Accompanied by Marked Monoaminergic Depletion [Article Summary]
Abstract
The study sought to unravel whether prolonged self administration of methamphetamine interferes with the level of dopamine and serotonin in rats. The rats were place in a lit chamber in which they were allowed to self administer meth. The researchers regulated the duration of the self administration session to achiever long and short access which the main variables in the experiment. The researchers discovered that long and short access to meth result ...
