Summary: The interaction between the limbic system and the subcortical dopaminergic system, is important in the experience of reward by the individual. The hypothesis in the present study is that, increased excitability of the medial prefrontal cortex, exerts a suppressive effect on the interaction between subcortical dopaminergic system and the limbic striatum structures (Ferenczi et al.). Lack of a reward seeking behavior is seen in patients with depression and MRI studies in these subjects have identified increased excitability of the medial prefrontal cortex. This finding was suggested as a rationale for the study. The experiments were designed to demonstrate ...
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