(Course No.) (City & State) Growing cells are located within defined environmental niches and any area outside the niche is very hostile. Because normal cells lack survival techniques, it leads to anoikis. The tumor development process strives when malignant cells escape from the local issues and resist anoikis. The cells of the immune system play a dual role of stimulating adaptive immune responses against tumor-specific antigens and at the same time promoting tumor angiogenesis and progression. This is through the support of the innate and inflammatory responses (Ravi et al., 2000). Integrins are termed as a family of adhesion ...
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Lymphatic System
The lymphatic system is an extensive one way drainage system, which is made up of lymphatic vessels, lymph nodes, the spleen and the thymus. It is part of the circulatory system. The lymphatic vessels have three main functions. Lymphatic vessels drain water and plasma protein that leaks from the capillaries and return them to the circulatory system, they carry fats absorbed in the small intestines to the blood, and transport cellular remains, pathogens, and foreign cells to the lymphoid tissues where white blood cells annihilate them (Starr. C, Targgat, Vers & Starr. L, 2012). Lymph nodes act as sites for ...
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