Essays on Molecular Weight

Drug metabolism is the enzymatic break down of drugs-a process that takes place in the liver. While drug metabolism can take place at the cellular level, the liver is the major site for this process due to its size-translating to a big supply of enzymes. Drug metabolism is classified as one of the liver’s processes to detoxify the body or get rid of foreign compounds (Law et al., 2014). When the drug reaches the target site and finished working, the remaining amounts may accumulate in the body to levels that may be poisonous or toxic. Drug components are ...

Seminar: Inflammatory and Immune Mechanisms in Lymphatic Vascular Disease

The YouTube video presented by David Zawieja, talks about immune and inflammatory mechanisms that occur in Lymphatic Vascular diseases. The lymphatic system has a significant role in various essential mechanisms inside the body such as edema resolution, fluid and macromolecular homeostasis, inflammation and antigen trafficking. The primary of the Lymphatic function involves the transportation of Lymphatic substances from the interstitial spaces between the tissues via lymphatic capillary network and nodes that terminate into the venous blood inside the veins. The most significant segment of the lymphatic function is the flow of lymph through multiple nodes. The immune cells like ...

In addition to the direct physical manifestation of swarm phenotype –increased length and number of flagella, swarm cells often produce wetting agent, usually a surface of some type, for instance, the surface in Serrtia (serrwettins) and Bacillus (surfcatin) (White, 2006). In both cases loss of surfactant dramatically decreases swearing proficiency in Bacillus as well as strains of E. Coli do not make surfactants, which is probably why they are such picky swimmers. Surfactants act mainly to maintain surface wetness, which in turn allows cells to swim in every shallow layer of fluid on the surface. Research findings indicate that ...

The term organic semiconductor is used for denoting the class of materials that are based on carbon, which takes part in semiconducting characteristics. And therefore, many of the attractive optoelectronic features exhibited in organic semiconductors emerge from the properties of carbon atoms. Organic semiconductor materials fall into two broad categories, i.e., low-molecular weight organic materials and polymers (Ishii et al. 2009). The individual energy properties are different as can be seen below. The bonding nature manifested in organic semiconductors is fundamentally dissimilar from those seen in their inorganic counterparts. The solid molecular crystals of organic semiconductors are bonded with ...

Assumptions in Molecular Weight Determination and their impact on MW determination

DSC measures the quantity of required heat necessary to melt a sample where the heat of fusion is calculated based on a percentage of crystallinity. Therefore, the methods used to measure crystallinity, weight determination such as DSC must be detailed to retrieve valuable results. However, in most of the molecular weight determination methods, there are certain assumptions undertaken but those assumptions also have a certain impact on results. In DSC profile, three types of distinct probabilities of uncertainty exist. The first is natural uncertainty that may be linked to equipment such as uncertainty of weight measurements of the sample. ...

Panther I.D.:

“The expression of ampicillin resistance and luciferase enzyme genes by E. coli transformation using the pUC18 and lux plasmids” Abstract The transformation process allows the uptake of DNA from the environment, with the incorporation and expression of genes. During this process, changes in the DNA of the receptor cell occur, producing some selective advantages in some cases, such as resistance to antibiotics. pUC18 and lux plasmids were used to determine the transformation process in Escherichia coli. Cells were made competent by the addition of calcium chloride and heat shock in order to induce the incorporation of the ...

Pyrogens are agents produced by bacteria, molds, viruses, and yeasts, which are known for causing fever and fever-related illnesses (Yaman, 23). Pyrogens tend to cause fevers by causing unprecedented rises in body temperature, which then leads to fever. This is usually a response by the body when fighting against an infectious disease. Pyrogens are thus produced, where they travel to the brain and disturb the hypothalamus which regulates temperature(pg. 24). Since pyrogens are harmful when they are injected into human bodies, they have to be minimized. The process of removing pyrogens in pharmaceuticals is called depyrogenation. It is ...

Chemistry

2. The nano carrier needs to remain in suspension in H2O, PBS, human serum, etc. What type of polymer do you need to use to decorate the surface of the nanocarrier to achieve this goal? In order to maintain the nanocarrier in suspension in water, Phosphate-Buffered Saline (PBS), human serum a suitable solution a polymer is needed on its surface. The polymer used needs to accomplish three goals. The polymer needs to decorate the nanocarrier surface to enhance suspension and secondly, to prevent protein absorption. Another characteristic is that the polymer evades the immune system. PLGA poly(lactic-co-)glycolic ...

Chemistry

Trizivir: Ingredients: 3 synthetic nucleoside analogues with inhibitory activity against HIV-1. “A recently approved antiretroviral looks like a nucleoside reverse transcriptase inhibitor (NRTI), but it acts like a protease inhibitor” (Portyansky 1999).

Active Ingredients:

1. abacavir sulfate, 300 mg (aka Ziagen™) 2. lamivudine, 150 mg (aka EIVIR™ or 3TC™) 3. zidovudine, 300 mg (aka RETROVIR™ or azidothymidine, ZDV or AZT because of Azide functional group).

Additives:

1. titanium dioxide 2. hypromellose 3. yellow iron oxide

Coating on Tablets

Is FD&C Blue No. 2, hypromellose, polyethylene glycol, titanium dioxide and yellow iron oxide

Inactive Ingredients: 1. sodium starch glycolate ...