The Relationship between H. Pylori Infection and Mitochondrial Microsatellite Instability in Gastric Carcinogenesis
Recent research has established that while there are a number of steps that take place in the development of gastric cancer, Helicobacter pylori (H. pylori) plays a major role. However, the mechanism of the influence remains unidentified. Researchers Ling et al. (2016) conducted a study to determine relationships between an infection of H. pylori, IL-8, and mtMSI and whether there is a trigger that causes the infection to progress to intestinal metaplasia, dysplasia, and ultimately to gastric carcinogenesis. The method used by the researchers included fresh samples from resected gastric cancerous cells and comparison samples of potentially pre-cancerous mucosa; ...