Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) are prearranged sections in bacterial as well as archaeal genomes, which form part of an adaptive immune system against phages —viruses that infect bacteria but not humans. CRISPR and CRISPR-associated (Cas) systems have been rapidly emerging as an alternative genomic editing tool to ZFNs (zinc-fingernuclease) and TALENs (Transcription activator-like effector nucleases). In the article, “Targeted mutagenesis in rice using CRISPR-Cas system,” the author applies CRISPR/Cas system in rice (Miao, et al.). The author investigates whether the CRISPR/Cas technology can create double standard breaks (DSB) in rice callus. The successful application of CRISPR/Cas ...
Essays on Mutagenesis
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