Essays on Neurodegeneration

Marcason W., What are the Components of the MIND diet? Journal of the Academy of Nutrition and Dietetics. 2015; 115(10): 1744

exercise? Movement Disorders. 2015; 31(3): 299 This is the first randomised control trial aimed at assessing the role of multi-domains in the reduction of cognitive decline. 1,260 participants aged 60 to 77 were involved in the two-year study. The multidomain assessed included management of metabolic and vascular risk factors, social abilities, cognitive training and an exercise program. At the end of the study, it was found that cognitive function of the intervention group ...

Its role in Microglia causing dopamine cell death

This assignment is being submitted on June 18, 2015 Introduction The list of prominent neurodegenerative disorders has Alzheimer’s at the topmost level and closely following it is the Parkinson’s disease. The latest researches pertaining to the Parkinson’s pathogenesis have narrowed down to the crucial relevance of Neuroinflammation and establishment of microglia. Thus there has to be a concrete substantiation to prove that Neuroinflammation has a significant contribution in causing Parkinson’s disease and other neurodegenerative diseases. Another approach to ratify the same can be done by proposing that genetic deficiency is not the sole cause for ...

The use of marijuana for medicinal purposes, a social or political issue, seems to be in question. The opponents to the use of marijuana for medicinal purposes stick to the same argument of social and at times religious effects. The support of the movement seems to be basing all evidence in the far-reaching uses of cannabis beyond medical application. With Washington and Colorado both recently legalizing marijuana for recreational use, it reopens the debate about whether or not marijuana should be legal for medicinal purposes in the United States. A look at the current research, an analyzing the argument of ...

Discuss the relationship between the cognitive and the biological features of Alzheimer's disease

In order to know the relationship between the cognitive and the biological features of Alzheimer’s disease, it is very important to know the definition of Alzheimer’s disease. Alzheimer is defined as the developed form of dementia that usually begins at the age of 40 years onwards. It usually begins when a person has problems speaking and remembering things and eventually the patients becomes very helpless and dies (Jon et al., 2013). According to its history, in 1906 the first person to talk about this disease was Alois Alzheimer. Following his discovery, the disease was later named after him ( ...

Amyotrophic lateral sclerosis (ALS): A summary

Introduction Amyotrophic lateral sclerosis is a rapidly progressing neurodegenerative disease. It is also known as Lou Gehrig’s disease. It is a disease that targets the neurons (nerve cells) that control the voluntary muscles. ALS belongs to a class of neurological diseases known as the motor neuron diseases (MND). Motor neuron diseases involve the steady deterioration and death of motor neurons. Motor neurons function as the communication links between the voluntary muscles of the body and the nervous systems. These neurons are located in the brain and the spinal cord. Transmission of information and messages occurs from the motor neurons of ...

Introduction

The use of marijuana for medicinal purposes, a social or political issue, seems to be in question. The opponents to the use of marijuana for medicinal purposes stick to the same argument of social and at times religious effects. The support of the movement seems to be basing all evidence in the far-reaching uses of cannabis beyond medical application. With Washington and Colorado both recently legalizing marijuana for recreational use, it reopens the debate about whether or not marijuana should be legal for medicinal purposes in the United States. A look at the current research, an analyzing the argument of ...

INTRODUCTION

The human body consists of tissues and organs that contain over 200 different cell types.1 these cells carry out all the functions required for viability and reproduction. It was argued long ago, that in some tissues, the differentiated cells have a shorter life span and that they are not able to self -renew.2 This led to the notion that such tissues are maintained by cells that have an extensive renewal capacity, and the ability to differentiate and generate daughter cells. These cells were termed as ‘stem cells”.2 Stem cells generate only the differentiated lineages of the tissues they reside in, ...

Prions are infectious proteins that are usually linked with the occurrence of neurodegenerative disorders in humans as well as many other mammals. They belong to the class of misfolded proteins and are the causative agents for the different transmissible diseases, mainly encephalopathy that can be defined by the changes in the anatomy accompanied by Pathophysiological origin that follow Mendelian genetics. The main characterization of the disease is the aggregation of proteins in the neurological system leading to degenerative brain diseases that are fatal and are incurable at present. Murray et al. (2004, p.37) have stressed that the transmissible ...

Abstract

Tay-Sachs disease (TSD) is a group of autosomal recessive lipid lysosomal storage disorders caused by mutations of the HEXA gene, which codes for the alpha subunit of the enzyme Hexosaminidase A, one of three enzymes responsible for the normal degradation of GM2 ganglioside, a substance found in high concentration in the plasma membrane of neuronal cells. The classic acute infantile form, discussed here, is a neurodegenerative disorder with onset at four to eight months of age in which acquired capabilities are lost and general neurologic deterioration occurs, with death by age two to four years. It occurs with highest frequency in the ...