The significant loss of blood calcium commonly characterizes the condition of hypocalcemia. In particular, the loss of calcium is common in the extracellular fluid, and it occurs in greater quantities though it is replaceable by the intestine or the bone (Watad et al., 2016). The condition is a consequence of various clinical entities with the signs and symptoms of neuromuscular irritability. The common conditions of the neuromuscular irritability include the paresthesia, laryngospasm, muscle cramps, seizures as well as tetany. The same instability of the neuromuscular structures appears in the elicitation of the Chvostek’s signs and the common Trousseau’ ...
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Muscle contraction is a very important activity that enables an organism perform various bodily movements and flexible actions, in response to nerve stimuli. Muscle fibers are multinucleated long cylindrical cells that have an outer membrane called sarcolemma, and are mainly composed of contractile elements called myofibrils (Dougherty, 2016). Myofibrils are made up of repeating units called sarcomeres. Sarcomeres in turn are composed of (thin) actin and (thick) myosin protein filaments called myofilaments (Dougherty, 2016). The muscle fiber structure and organization is shown in Fig 1.
Contraction Mechanism – Sliding Filament Theory
According to the sliding filament theory, during contraction myosin filaments remain constant in length, ...
Myasthenia gravis (MG) is a type of neuromuscular disease that causes certain muscles to fatigue and weaken. The disease is considered to affect voluntarily controlled muscles such as those involved in chewing, facial expression, speaking, eye and eyelid movements and swallowing. The disease occurs in all sexes and age groups. However, it commonly affects women under 40 years and people aged between 50 and 70 years in both sexes, though it is known to affect older people at large (Sieb, 2014). Within the UK, it is estimated that in 100,000 people, there are 15 cases of the disease. ...
Biofeedback, according to Mayo Clinic Staff is the process by which one gains control over some of the involuntary body functions and this later translates to healing. It involves measurements of a person’s physiological and biomechanical aspects that are taken and then utilized in the treatment of various illnesses. These measurements include the cardiovascular system, respiratory, or neuromuscular aspects. One of the tests that are likely to be carried out is ultrasounds. These tests are mostly carried out immediately a patient checks into a health clinic having either an accident or health condition such as hypertension or cardiovascular ...
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Basketball is one of the most dangerous team sports in the world with over 1.6 million basketball-related injuries reported every year and over three acute injuries occurring in every 1000 hours of basketball exposure (Luig and Henke, 2011). Most people including basketball players and coaches do not know these facts because excessive contact and aggressiveness are prohibited in the sport. Basketball’s popularity is growing in most parts of the world. It is estimated that over 300 million people worldwide play the sport because of its simplicity and minimal requirements. As the popularity of the sport ...
CHAPTER I
THE NATURE AND SCOPE OF THE PROBLEM Introduction As far as human walking is concerned, it has been best described as the progression of the body’s center of mass along a pathway by moving the two legs alternatively. It is generally acknowledged that the development of walking skill in human beings is completed by the age of five (Sutherland, 1980). Locomotion is influenced by interactions between neuromuscular activity as well as musculoskeletal alignment (Perry & Burnfield, 2010). In addition, there are several other factors that can affect the coordination pattern of walking. These include sensory information from somatosensory, visual ...