The movement of cholesterol, which is unestrified, is largely due to the activation of the NPC 1 protein. In cases where inactivation of mutation of this protein occurs, one may be suffering from Niemann-Pick type C disease. So what is this disease? Niemann-Pick Type C disease is a serious but rare nuerogenerative disorder. It is very common to children at or approaching adolescence. The disease is estimated to infect one out of every 160,000 children (Patterson 2009). NPC is regarded as a malfunction in the body’s cholesterol metabolism. NPC is also is sometimes referred to as childhood Alzheimer. This ...
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