Essays on Parkinson

Neurodegenerative Disorder

Introduction Neurodegenerative disorders refer to debilitating health care complications that occur because of slow degeneration of nerves cells. Neurodegeneration process is the progressive deterioration of structure and functionality of neurons in human body systems (Kovacs, 2016, 189). Ideally, neurodegenerative disorders represent the long-standing challenges in the field of basic science and clinical medicine. This is because of the persistence showed by the illnesses despite the unending attempts to adopt solutions to mitigate their health effects and severity on patients. The diseases affect the neurons in the human brain. As a result, it causes instabilities in the brain and spinal ...

Parkinson’s disease lacks a cure but certain medicines can help manage the symptoms. These medications function to offer a substitute for dopamine, the signaling neurotransmitter in the brain. Carbidopa-levodopa is hitherto the most effective medicine to manage Parkinson’s disease. This chemical moves to the brain and is converted to dopamine. The chemical levodopa is mixed with carbidopa preventing it from being converted to dopamine prematurely out of the brain hence potential side effects such as nausea are lessened. Potential side effects with this medication however include orthostatic hypotension or feeling light headed and nausea. With continued use ...

Introduction – Case Background

The Regency Plaza is a hotel complex that comprised of 300 rooms and approximately 96 luxury condominiums. The project building was the combined structure of steel and concrete, which made the structure solid and reliable for mass capacity. The regulatory of the project, the Regency Hotel Group owns and regulates 24 luxury hotels that are situated in the prominent urban cities globally. They regulatory charges $550 each night for rooms and the Regency Plaza is the first condominium project of the entity. Discussing the role of Kris Hodgkins, the regulatory hired her services that were accountable for designing, construction, ...

John Magill is a 75-year-old male with Parkinson’s disease, which he was diagnosed with five years ago. John was admitted to the hospital after falling at home. The physical examination revealed bruising on John’s hips and buttocks, as well as a tear on the right hip, but the X-ray did not reveal fractures in the lower extremities. The emergency department noted generalised tremor, decreased mobility, signs of confusion, agitation, and restlessness. The assessment of John’s vital signs showed that most measures are within expected ranges for an elderly person (temperature 37.2; respiratory rate 24; heart rate ...

Introduction

The case dwells upon the situation, in which a new Major Accounts Management, Zain, who recently joined the organization Zoro Stationary, found himself, ones trying to adjust to the new environment. The reality demonstrates that the previous experience of this professional, which encompasses over ten years in one of the major regional clothing and household retailers allowed good insight into the purchasing and customer behavior. The challenges, associated with the change of the industry, corporate culture and personal diversity, however, built on a number of difficulties in adapting his skills to the new role. The learning process within the ...

1. Introduction: Concussion occurs from traumatic injury to the brain and results in a temporary disruption of brain function or loss/altered consciousness for a short period (Moser, 2012). Concussion is common in contact sports, where there is a collision between players. It is expected to have an adverse cumulative effect on the persons cognitive and mental functioning (Moser, 2012). With course of time, this could adversely affect once athletic career. Identifying incidence of concussion in a particular sport, will help to determine risk and initiate preventive measures. Rugby is a full body contact sports and there are high chances ...

There are many affective, cognitive, and social functions of music that have been identified and covered in many types of research conducted in different countries. The increasing concentration and attention are the cognitive reasons of music being crucial and bond, and group cohesion is one of the social reasons (Krumhansl, 2002). The level of a person’s well-being varies among individuals, and his/her links with music are due to reason that could be different from others. The music is vital and a must component to achieve effective wellbeing. The music generates positive outcomes in almost every individual (MacDonald, Kreutz, & ...

Stem cell research and therapy are not new and continue to be a controversial topic. The benefits of stem cells, and what most scientists agree are the potential benefits of stem cells, in curing disease and regenerating tissue are seemingly limitless. In the past bone marrow transplants were the primary method used to obtain stem cells for research into cures for contemporary diseases such as cancer, heart disease, Parkinson’s, Alzheimers, multiple sclerosis, and diabetes as well as spinal cord injuries. However, Embryonic Stem Cell Research (ESCR) is much more controversial. There has been a recent shift to use ...

Muhammad Ali

Everyone has their own prototypes to follow such as idols, parents, friends or neighbors with motivating and inspiring life experience. World history has various examples of the famous persons’ biographies and after its reading people are inspired for accomplishing any goals. It can be people who lived a century ago or our contemporaries. Someone considers sportsmen to be successful, others find politicians, entrepreneur or singers more inspiring. However, they are united by the common trait, which is leadership. Nowadays, when the world is changing rapidly, the ideas of those leaders continue to be relevant and contribute to the people ...

1. Identify a problem and explain the problem: Background: The project proposal is related to the prevention of fall among elderly. The incidence of falls is high among the elderly population. Studies suggest that elderly who fall once, are more likely to fall in the future. A number of conditions like poor eye vision or transient ischemic attacks or pets or general body weakness or other miscellaneous reasons, can increase the risk of fall in the elderly population. Falls can be particularly serious and life changing for elderly. It can make them dependent on others and also increases the ...

As adults, there are times when we reflect on our childhood years and feel very emotional about situations whereby those vested with our care and protection failed to consider what was in our best interest. More often than not, children feel that their voices are not being heard, that they are being treated unfairly or that their real problems are trivialized and sometimes ignored. Child advocacy is all about speaking out on what is in the best interests of children, their needs and rights. Some of the issues in child advocacy include child abuse, foster care, parental substance abuse, ...

Today’s ageing Workforce and Labor Shortages

Canada is witnessing a change in its work force – the percentage of workers aged above 45 has changed from 27% in 1993 to 40% in 2010; a phenomenon that is compelling the experts to re - examine the common beliefs about an aged work force. The Canadian demography is heading towards an increase in senior population with its baby boomers – those born between 1946 and 1965(Parkinson, McFarland & McKenna, 2015), reaching retirement age. Parkinson et al, (2015) predict serious implications on the Canadian economy, Government policies and the well being of Citizens unless significant adjustments are made to address ...

Ang Lee is director of wide range of films, and each of them provokes controversy and interest among the audience and critiques. In every taken film the sequences are combined in a unique narrative with its questions and much less answers. Lee is a representative of so called independent genre, meanwhile it should be noted that his films could hardly be titled by any kind of clichés (Siraganian 1). Nevertheless, having in mind the alternative, not common point of view and the craft of directing, all his films are definitely independent. The core essence of Ang’s style ...

There are different periods in the history of countries that play more or less significance roles. No doubt that First and Second World Wars immensely influenced the life and political situations almost in every country. These were the most disastrous event and their aftermaths were often disastrous too. In spite of these tremendous periods in the world’s history there were no less and maybe, according to some views, more important period in the history of America in the twentieth century. The period of the 60s is treated now as the time of innovations in culture, science, music and ...

The films that will be examined in this paper have much in common though, at the same time they consist of different aspects in their plots and picture different characters (Hayward 67). The main issue that unites all these films is the theme of obsession. The meaning of this word in films is the same, but considering each character, it may have slightly different understanding. Each character has different aims and values and they act according to them (Parkinson 109). Nevertheless, there is one common and the most important characteristic feature in their behavior. It influences their lives and ...

John Locke’s Social Contract Theory:

Introduction: The Social Contract Theory argues that people’s morals and obligations depend on an agreement among them in order to form the society in which they reside. John Locke's argues that the state of nature of man is perfect, and no one is to interfere each other’s’ lives. He states that even though the state of nature is one without punishment from the authority, it is not pre-moral (Friend, 2004). In Hobbes's argument, he points out that without identification and recognition of a universal authority, chaos is the order of man. In contrast to this, Locke and ...

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Introduction

Parkinson Disease (PD) is a very complicated neurodegenerative condition including the motor and non-motor manifestations that lead to neuronal loss. Currently, only symptomatic therapies are available but nothing is known yet to prevent this degenerative process. This is a multi-factorial condition with multiple risk factors that includes increasing age, genetic vulnerability, and environmental determinants. All these factors mutually play a role in the pathogenic process of PD. Medical sciences have achieved major advances in understanding the process working behind PD development that are Nigral Dopaminergic Apoptosis, Protein ...

Abstract

This paper is about the investigation of Parkinson’s disease, and in particular is involved with the examination of its symptoms, stages, causes, prevalence, diagnosis and treatment, and social impacts. Finally, the paper analyzes and evaluates two ongoing on Parkinson’s disease researches, which are also examined in respect to their impact on Parkinson’s disease patients. Key words: Parkinson disease, Parkinson disease causes and impacts, Parkinson disease symptoms and prevalence, Parkinson disease diagnosis, and Parkinson disease ongoing research.

Idiopathic Parkinson disease (PD) is a progressively evolving disease with main manifestations resting tremor, muscle stiffness, slow movement and loss ...

In this paper we will be dealing with the important contemporary issue which consists in correlation between the social media activity and civil society as well as radical movements’ response to it. The accent will be put on such informational giants as Facebook and Twitter as well as concrete individuals, who use these resources in order to reach their own goals. We are aimed at answering the question what role of social media is. Additionally, social media will be looked through a prism of current political debates and primaries, threat of terrorism and certain other phenomena. The issue of ...

Many people suffering from this disability do have unusual styles of studying, listening to people and a different interpretation when communicating (CDC 3). Scientist studies show that it is a disease that is common in boys than in girls and can be examined in an ethnic or racial group. It is characterized by behaviors such as hand flapping, résistance to environmental change and aggression (ASF 4). Autistic people have been shown to succeed in life with plenty of significant people being named to help give guidance to the young ones that are autistic. The main reasons as to ...

A significant population in the world smoke cigarettes, which is a harmful behavior. Various studies have indicated that smoking is among the leading but preventable causes of death and diseases around the world. Apart from health issues produced by smoking, financial issues also prevail and they are among the main predictors of quitting smoking. For instance, Sindelar and O'Malley (2013) found out that quitting smoking could help an individual to save about $3000 per year. Despite the financial, environmental, and health problems created by smoking cigarettes, many people argue that smoking provides various benefits, and they cannot imagine the ...

Abstract

Nowadays, the importance of studying the ancient literature becomes an actual question. From year to year, an amount of worth studying contemporary literary works increases and a lot of students complain that they do not want to read and analyze literary works of the ancient authors. However, they forget that the ancient literary works were the first examples of literature in the history of humankind. They contain information about life and environment in the preceded days and inspire a lot of young writers. The aim of this paper is to prove that the ancient literature is a basis for ...

Introduction

Environmental adaptation is essential to the survival of any animal. In fact, this attribute helps organisms obtain nutrients, build homes, withstand extreme weather conditions, attach mates and enhance their safety (Nelson et al. 2008). With this in mind, it is worth appreciating the fact that polar and grizzly bears have different physical and behavioral characteristics due to environmental adaptation in spite of their species similarities. The polar bear is specially adapted to survive in the cold pole regions. Its body structure and genetic composition have substantially evolved to accommodate the low temperatures and harsh environmental conditions. Its behavioral attributes ...

The title of the paper that is reviewed is: “Sumoylation and Phosphorylation of α-synuclein”.

It is a research article that explores the molecular mechanism underlying αSyn toxicity. αSyn is a protein that is seen in the inclusion bodies of dopaminergic neurons in patients with Parkinson’s disease. Parkinson is an important neurodegenerative disease, and the cure of the disease is still unknown. In-depth understanding of the molecular pathogenic of the disease will help in determining suitable cure. Through the insight obtained from a literature review and previous studies, the authors identified that post translational modification of αSyn, could affect its physical characters like the ability to form aggregates, solubility in cytoplasm and its ...