The activity of AMPK supports the normal function of the endothelial barrier (Xing, Wang, Coughlan, Viollet, Moriasi, & Zou, 2013), while on the other hand, the exposure of LPS ensures that there is inhibition of AMPK, thus accentuating lung injury and endothelial barrier dysfunction (Kratzer et al., 2012). It is a fact that LPS increases the permeability of the endothelium, which occurs once there is a decrease in the AMPK activity. This is consistent with the fact that the activation of AMPK activator, AICAR, emphasizes LP, once it is applied in vitro to test the hyper endothelial permeability. Experiments done ...
Essays on Phagocytosis
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Introduction and Overview
The Rhesus factor (Rh) refers to the red blood cell’s(RBC) surface antigen;the name Rhesus comes from the small Indian monkeys in which it was first discovered. Rh incompatibility,sometimes referred to as Rh disease, is a condition that occurs when a woman with the Rh-negative blood type is exposed to Rh- positive blood cells, leading to the development of Rh antibodies. This condition can have fatal outcomes including haemolytic disease of the foetus or newborn, autoimmune haemolytic anaemia and haemolytic transfusion reactions (HTRs). These conditions have, in the past, raised a lot of concerns, and some ...
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