Essays on Polymorphisms

Introduction

Cancer is a disease that is associated with high morbidity and mortality rates. The Prognosis of the diseases in many of the patients is also poor (Adorno & Brownell, 2014). The Economic cost involved in treating the conditions and other factors serve as an incentive for studies into approaches for the identification of high risk people. The development of brain metastases in patients diagnosed with lung cancer further amplifies the disease burden (Adorno & Brownell, 2014). This paper summarizes two articles in which the authors present content on the use markers in the identification of high risk populations.

Summary of Articles

The article by ...

Drugs can have many differing affects on people, whether their consumption leads to a positive or adverse response. All of this depends on the levels of enzymes in the body and how the variations of expression lead to these possible outcomes. The major theme of the two sources on this topic relate to the specific enzyme, CYP3A. CYP3A is a subfamily of cytochrome P450 enzymes, which serve to catalyze the addition of oxygen into molecules. Their ultimate role serves two spectrums: to convert foreign substances into less toxic products that can be eliminated from the body, or to convert ...

The video reflects on the molecular level interactions of genes being dependent on the diet and the environment. The diet we intake decides the nutrients that our body receives and perceives for involvement in metabolic processes as the enzymes and other factors need vitamins, cofactors, minerals as subordinates to play their roles. A bowl of green leafy vegetables, for example, offers many such nutrients to fulfill the needs of the body. Single nucleotide polymorphisms (SNPs) are the difference of a single base in the sequence of a gene that varies in individuals of a population making each one unique ...