Essays on Polypeptide

Introduction

Sickle Cell Anemia or Sickle Cell Disease is an inherited blood ailment. Those suffering from Sickle Cell Disease have abnormal S/ sickle hemoglobin in the red blood cells. Hemoglobin is the protein in the blood that aids in carrying oxygen throughout the body. The ailment takes its appellation from the shape of the red blood cells of a person affected by Sickle Cell Disease, which have the shape of a sickle. They are stiff and adhesive rather than a disk like normal cells. The misshapen cells tend to get trapped in the small blood vessels hindering the movement of ...

Abstract

This lab report discusses the Cellular Location of Metabolic Enzymes. Regarding methodology, the experiment was conducted in three sessions during the first session liver homogenate and cell functions were prepared. The first session was carried out by homogenizing the liver in an isotonic media. The Maltase and lactate dehydrogenase were determined in the second session, and protein concentrations were estimated in the third session. The Maltase dehydrogenase (MDH) and Lactase dehydrogenase (LDH) were used to catalyze the reactions in session two. The biuret reaction was used to estimate the protein in the last session. The relationship between absorbance at ...

Lysine

Amino acids are organic molecules, the monomers of proteins that contain both amino and carboxyl groups. Proteins of a cell mostly contain 20 types of amino acids that differ in the side chain known as R group. Therefore, the properties of the amino acid in protein fully depend on the characteristics of the side chains.

Lysine is an essential amino acid, that means it cannot be synthetized in the human organism. The side chain of the lysine molecule contains an additional amino group attached to the carbon skeleton. Because of the positive charge in the side chain, the charge ...

Formation of bone during foetal development occurs through the process of ossification. This process is extremely important to proper bone length, density, and uniform skeletal formation. It is driven by a complex network of genes that code for signalling proteins whose function is to turn the ossification process on, off, or slow it down. Defects in these genes can cause problems with the ossification process, and can lead to conditions of skeletal dysplasia (improper formation of bone). One such condition is Achondroplasia, one of the most common forms of dwarfism, or congenital short stature (Lister Hill National Centre for Biomedical ...

Background

Early scientists and nutritionists believed that the most vital nutrient in living organisms, for building and maintaining the body was the protein. The role of proteins as enzymes came into existence several years later. This was around 1926 when experiments showed that enzymes were proteins. Insulin was the first protein to be sequenced. Hemoglobin was the first structure of proteins to be resolved. Myoglobin was then resolved later.

X-ray diffraction analysis (X-ray crystallography) led to the determination of the structure of the proteins (three-dimensional structure). The purification of proteins can be made possible from cellular compounds. Several methods have ...

Introduction

Cloning is a term used to describe different methods of duplicating biological materials. Plasmids can be used to ‘clone in a gene’ and then express a given protein in mammalian cells. The type of protein used here is called AWP1 protein which is associated with PRK1. This type of protein is a universally expressed protein and the AWP1 gene is switched on during the early development of a being. The AWP1 may play a regulatory role in the mammalian signal transduction pathways. The AWP1 posses a conserved zf-A20 zinc finger domain at its C-terminal. When it is expressed in COS – 1 cells, the Myc-tagged ...

Pain Management for the Obstetric Patient

Pain is subjective and individual responses to pain vary. The response of every client to labor pain is also unique. Perception and expression of labor pain is influenced by a number of factors. These factors include cultural factors, individual pain tolerance, anxiety, level of education, attitudes of the client towards pregnancy, age, and parity. Management of labor pain is a key goal of intrapartum care (Simkin, Lockwood, Eckler, & Klein, 2014). This paper will discuss pain management for the obstetric patient. It consists of two parts. The first part will focus on the causes and management options for pain and discomfort during ...

Introduction

As a multi-functional protein, Cytoplasmic Actin can be found in all eukaryotic cells at higher concentration levels of over 100 μM. It is the most abundant protein found in most eukaryotic cells, which makes it a critical player in different cellular functions, such as maintaining cell shape and polarity to transcription regulation. The structure of Cytoplasmic Actin is distinguished by a large number of polymorphic proteins which form the filaments. In eukaryotic organisms, such as archaea and eubacteria, actin-like proteins activities are related to sub-cellular organization, motility, cell shape maintenance and cell cycle progression; they are either associated to cell membrane or ...

Structure and Functions of Cytoplasmic Actin

Cytoplasmic actins refers to the conserved proteins. Actin can be found in all eukaryotic cells, and are involved in variety of cell motility. Protein structure is formed by combination of variety of amino acids by losing the molecule of water. Proteins get involved into variety of biological functions, and proteins have different types of structures depending upon the requirements. This paper intends to discuss different types of protein structures, their functions and other related aspects. The structure of proteins can be divided into three categories i.e. primary, secondary and tertiary. The structures of proteins are polypeptides-sequences that get ...

- Introduction Over the last 30 years, the term Human Growth Hormone (hGH) has predominantly been associated with performance enhancement and illegal usage in professional athletics. The stigma associated with this term has roused tremendous amounts of discourse in the medical and sports community alike (Martinez, 2012). Today, new insights have prompted an inquiry into how sleep and exercise may affect the human growth hormone. Researchers have discovered that poor diet, inadequate sleep and lack of proper exercise deplete the body’s ability to produce hGH. Deep sleep (lack of rapid eye movement) and heightened activity at the ...

Transfer factors are tiny molecules that modulate the activities of the immune system like Natural Killer cells, T cells, and immunoglobin antibodies. These molecules were discovered by Dr. Sherwood Lawrence and in the recent times 4life came to understand that extracts of pure transfer factor can be obtained from egg yolks, colostrums and got patents for the processes of the extraction. The 4life Transfer Factors products are health nutrition supplements which utilize Transfer Factors in supporting of the immune system better than any other source. This paper evaluates whether these dietary supplements can be used for management curing of ...

Introduction to proteins

Proteins are polypeptides made up of amino acids joined together by polypeptide bonds. The number of amino acids in a protein molecule can vary from several amino acids to thousands of amino acids. Proteins are made of a combination of several of the 20 naturally occurring amino acids as well as other minor amino acids. Proteins are very important molecules in the body .They form the structural components of animal and human tissue (Yildiz, 2009).

The primary structure of proteins is determined by the sequence of the amino acids in the protein. A functional amino acid must contain the correct sequence ...