Essays on Residue

(Author’s affiliation) Diabetes is a polygenic disease characterized by significantly higher levels of glucose in the blood. In this disorder, metabolic disorders lead to persistent thirst (polydipsia) and excessive level of urination (polyuria). Diabetes is caused by insulin-related disturbances in the body. In healthy human beings, pancreatic β cells have insulin that is found as a hexamer having three insulin dimers attached together by two central zinc ions. The insulin monomer has a 21-residue A chain as well as a 30-residue B chain. These chains are cross-linked by two disulfide bridges, i.e. CysA20-CysB19 and CysA7-CysB7. There is also a ...

Introduction

Cigarette collection systems comprise of the major ways that several companies including Tobacco manufacturing industries that help as one of the strategies in managing effect of cigarette butts in littering bins that is currently a big challenge in urban areas. According to Riutta, (2012), it is imperative to address this topic of issues concerning cigarette butts in our daily city lives because of the high negative impact they have on our environment, and thus health being one of the leading causes of preventable deaths. According to health analysts, cigarette butts are made from a fibrous material that is essential ...

The environment is everything that surrounds us. It involves not only the natural elements that the word “environment” entails but also people and the man-made components of the world. Nor is the environment restricted to the outside, it also involves the indoor sections in which we live and work. The environment, therefore, is much more than simply the ozone layer and the ocean. It is the soil, air, water, lands, animals, houses, restaurants factories and all that they contain. Anyone who uses pesticides indoors or outdoors, in a city or a country, needs to consider the way that pesticide ...

An Assignment Submitted by

GMOs (Genetically Modified Organisms) are used for a wide range of different purposes: production of pharmaceutical drugs, experimental biology and medicine, and, of course, agriculture. The latter is the most controversial because it is directly connected to consumption. The most popular GM foods in US are corn and soybeans (Johnson & O’Connor, 2015). Corn is the most widespread GMO product in the world, but a very little part of it is sold on the cob. Large amounts of it are used to produce ingredients for different processed foods and drinks, especially corn syrup, rich in fructose, and corn starch. ...

Synopsis:

I witnessed the body of a victim lying supine on an outside deck on arrival to the location of the reported shooting. From observation, it is evident that the victim is an elderly man since he has grey hair. The victim is dressed in a blue jacket (that is zipped up past the halfway point), blue shirt, and blue pants. The victim is wearing wire-rimmed silver glasses with blood spatter on the left lens. Closer examination of his face reveals that there are numerous evident blood spatter patters below his nose on his upper lip, chin, and upper left ...

- Bookmakers owning series of betting shops. The customers will be available in the shops for betting on horse race. A sample data was collected from 150 shops. In that 50 days are Saturday and 150 days are week end. The scatter plot has been plotted between the expenditure per customers against the number of races and against the square root of races. The scatter plot against the expenditure per customers and the square root of races fits the best linear regression graph than the number of races. In statistics the slope of square roots makes the best fit ...

PSTD and Religious Faith

Combat PSTD and Religious Faith According to Dr. Nelson-Pechota (2004), every war has been virtually fought with a religious foundation. Faith in the divine powers has helped soldiers to confidently stride to a battle. Their religious faith has strengthened their courage and convictions. They also believe that they are favored or empowered by God when they meet with success in the battlefield. However, wars also create a moral confusion due to the combatants’ religious influences. As such, they find it conflicting to perform an act of violence which might be a sacred duty in another instance.

For combatants, intrusive thoughts and ...

Agriculture has been a part of man’s life ever since it was discovered that we could grow the food that we consume from one place and not just leave every time our resources were utilized. As science and technology progress together with agriculture, we came to realize that we could actually manipulate things like environment, amount of water, the type of soil, etc. in order to gain more crops.

The United States, as one of the top developed countries in the world, developed several techniques to which will give the highest benefit without harming our environment. These include crop ...

Protein degradation is a regulatory process of all living beings that helps to weed out proteins that are faulty in nature. The fault maybe in their sequence or folding. The proteins are degraded via ubiquitin-proteasome system (UPS). The proteasome is made up of an outer activating module and an inner core particle (CP), which in turn is made up of outer α subunits and inner β subunits. The α subunits guard a N-terminal gates pore, which open up when proteasome activators (PA) binds to it. The β subunits have the active sites that can broadly accommodate different faulty proteins for degradation. ...

Question 1

The solar system is situated in the outer reaches of the Milky Way Galaxy. The Milky Way Galaxy is a spiral way and is made up of over two hundred billion stars. The Milky Way Galaxy has many arms which are named for the constellations seen in those directions. Examples of the spiral arms within the Milky Way galaxy include the Sagittarius arm, Centaurus arm, Perseus arm, Cygnus arm and the Orion Spur arm. Our solar system is located in a spiral arm that is called the Orion Spur. The Orion Spur is named after the constellation “Orion the hunter”. The ...

Introduction

CD4 is a cellular immune response co-receptor that raises the avidity of relationship between an antigen-presenting cell and a T-cell through interaction with non-polymorphic parts of the complex between T-cell receptor and major histocompatibility class II molecules. It directly contributes to transduction of signal via cytoplasmic relationship with the lymphocyte kinase. CD4 also plays a role as the high-affinity receptor for attachment of cells as well as entrance of HIV. The CD4 extracellular part consists of domains that resemble immunoglobulin D1 to D4. This component of the CD4 has been qualified as a recombinant soluble protein, and crystal structures have been identified for ...

1. When placed on an agar slab and incubated at 30°C for 2 days, a single yeast cell proliferates into a colony with a diameter of 2 mm containing 108 yeast cells. If the cell has a functional Ade2 gene (Ade2+), the colony will be white; if Ade2 is non-functional (Ade2–), the colony will be red. You take a strain with a mutant Ade2– at the regular chromosomal position (red colonies) and insert a second, functional Ade2+ gene near the telomere. You find that the colonies are a mixture of red and white patches or sectors. Figure 1 shows some colonies; the black regions represent the ...

Introduction

Initially there were beliefs that, MMPs are jointly able to degenerate all constituents making up the extracellular matrix (ECM) together with basement membrane that confines their operations to tissue reconstruction as well as the preservation. Nonetheless, the contemporary studies also signify that MMP-1 is responsible for controlling the production or else the activation of the chemokines. At this point, it is critical to understand that MMP-1 is among other MMPs. Similarly, the knowledge holds it that MMP- 1 cleaves a peptide bond beforehand a residue comprising of a hydrophobic adjacent chain, for instance Met and Leu. The other sideways chains cleaved ...

The aim of this essay is to plan and suggest an intervention plan for Henry. Henry underwent a temporary loop ileostomy approximately six months ago. The aim of this essay is to discuss the various aspects of peristomal skin care. The evidence for and against various products described for peristomal skin care will be reviewed and discussed. The intervention plan has to focus on reeducating the ostomate about good self-care practice for the peristomal skin. The peristomal skin is the skin that surrounds the stoma and the skin to which the stoma appliance adheres to. Patients who undergo ileostomy ...

Describe the conservation choices that you recommend for implementation on the farm.

There are numerous conservation choices that can be implemented in the farm. First, crop rotation must be implemented. For example, corn, legumes and small grains can be rotated. Scientific studies have showed that crop rotations that include small grains and alfalfa significantly reduces soil erosion. Likewise, choosing the right rotation of crops will also help reduce the use of pesticides. In planning the rotation, it is best to design the rotation in such a way that the farm will meet the farm needs and goals for the yield as well as prevent erosion. Crop residue management is also recommended. ...

Abstract

Crude oil, also known as petroleum, is one of the most important natural resources. It is a fossil fuel that is non-renewable and has different components such as hydrocarbon compounds and other materials like oxygen, sulphur, nitrogen, salt and water. It is normally extracted from the ground, under the seas, and on land and is then transported to refineries. Most of the substances are removed in the refinery, and the oil is broken down and blended into useful products (McCants, 1989). Some of these products include medicines, plastics, fabrics, dyes, cosmetics, and transport fuels. Transportation of crude oil is done ...

A chain of eleven random explosions has taken place in an area that traverses two states and seven counties. The random explosions resulted in five deaths, 32 injuries and significant property damage. In all eleven cases, the explosions were detonated remotely. The Virtual Police Department of Maryland (VDP) will be the lead investigative agency because the first three attacks were within its jurisdiction. Two suspects were recognized and arrested, one adult male and the other a teenage male. Search and seizures were exercised, and both subjects confessed to their respective roles in the collective crime. - Model: Investigative Taskforce ...

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Introduction and Literature Review

The value for a drug is significantly impacted by the dissolution rate, chemical stability and solubility of the drugs thereby impacting the pharmaceuticals efficiency as well. In the pharmaceutical industry multi-component crystals such as hydrates, solvates, co-crystals and salts have a major role during the design of new solids. Solid does not self-crystallize. It crystallizes in varied forms depicting random crystal properties. Various approaches are used to modify solids like Salting, Solvation, Hydration, and Polymorphism. Apart from these approaches, Co-Crystallization is a promising new approach to modifying solids (Nauha, ...

Introduction

Composition of Dietary Fiber Dietary fiber is an essential component in nutrition and health (Mora et al., 2013; Klosterbuer, Roughead, & Slavin, 2011). Thus, the present study will explore the effect of particle size and source of fiber on the level of cholesterol in the human digestion system. Primarily, dietary fiber is a constituent of plant foods and includes materials that have diverse morphological and chemical structure. Such materials resist enzymatic action in the human digestion system (Dhingra et al. 2012). In the gastrointestinal tracts, the dietary fiber forms a matrix that has both amorphous and fibrous characteristics. The matrix’s ...

The Current State of Research on New Methods and Technologies for the Safety and Reliability of Assessment of Propellants, Explosives and Pyrotechnics1

Abstract

Materials with high energy have in the past and are still in use for both intensive military and civil purposes. Research and studies have been conducted recently to try establishing and inventing new materials likely to have enhanced high performance and that are less sensitive to heat and shock as compared to existing materials. In future military applications have a threshold to be adjusted to. This paper is mainly focusing on the on the advancements, possible formulations of ...

Introduction

This is well documented that the chemical composition of water affects the taste, color, odor, and so forth. Some of these salts also pose a threat to human health. The chemical composition of water is based on different dissolved solids. Total dissolved solids are referred to matters in tap water or water bodies that left in a container as residue after evaporation and drying of a water sample. WHO and EPA recommended that it should be below 500 mg/L (Broséus et al., 2009; EPA, 2013).

Classification of Dissolved Solids

The dissolved solids comprised of various salt contents present in the water as well as other ...

Introduction

Aeolian processes occur in environments such as deserts, agricultural fields, and coastal regions. The features of such environments include a nonexistent or sparse vegetation cover, strong winds, and a supply of fine sediments. In Egypt, the increase in human population has led to the lateral spread of human settlements from the Nile’s flood plains to various locations in the western desert land. Such areas include the Kharga Oasis, where the government has initiated land reclamation projects for agriculture and human settlements. However, the developmental plans have missed the issue of natural hazards such as dune movements. Hence, the success of such ...

Education as a social phenomenon determines the development of human civilization, its progress or regress. The education system is a part of society, so society determines the objectives, content, form, and the whole concept of education; while at the same time affect its development. Currently, world focuses on the consistency of the educational and socio-economic development concepts (Anderson, Anderson, & Cherup, 2009). The observed global trend of sharp increase in the role of human factors in the development of post-industrial, information civilization, as well as national needs of society, the modernization and gradual integration into a single global community, make new, much higher ...

Dissolved Oxygen

INTRODUCTION Dissolved oxygen is a useful parameter used to determine the level of effluent in waste water treatment. Living organisms in water bodies require oxygen to break down organic matter. These organisms consume the dissolved oxygen in water and give out carbon dioxide. Oxygen does not readily dissolve in water and gets depleted quickly by increased micro-organism activity. To maintain optimal oxygen levels in a water body, the oxygen replenishing rate from the air should be equal to dissolved oxygen use by micro-organism in the water. A curve drawn to represent dissolved oxygen levels down a stream from a point of effluent ...

Introduction

A sustainable diet is the diet that has a good taste, and enjoyable to an individual such that an individual might not abandon it. The diet needs to be affordable and able to supply all the nutrients required for normal growth, reach and maintain good health at all times and also for the vitality. A sustainable diet can be continued over a long period. On the other hand, unsustainable diet is a diet that can make one feel too fat, fatigue or ill. Unsustainable diet leads to diseases if one follows it for a long period. In western countries, there is a concern over ...

Introduction

In the discipline of forensics, the field of ballistics is the “study of motion, dynamics, angular movement, and projectile units (bullets, missiles, and bombs). In the context of a criminal investigation, there are a host of possible applications to aid in the facilitation of a criminal conduct. Bullets that are discharged at a crime scene will be inspected in an attempt to discover pieces of evidence and information. Among the pieces of information that police hope to recover from the bullet are the possible type of gun used in the crime, whether the gun was used in a previous crime, and other information that ...

DNA DAMAGE

1. Introduction The p53 gene is a tumor suppressor gene that is activated whenever a cell is subjected to cell damage. The p53 gene determines whether a cell should survive a damage or should undergo apoptosis. These decisions are regulated by posttranslational modifications. Phosphorylation of the serine 46 residue is one such modification that is relevant to this study. However, it is unclear why a Ser46 phosphorylated p53 favors apoptosis over survival (Feng et al. 2006, p. 2812; Taira et al. 2014, p. 717). Studies have shown that the elusive molecular mechanism of Ser46 phosphorylation of p53 induce apoptosis in the tumor ...

English

There is a serious debate about what makes a healthy food. Many people argue that vegetarians eat healthy food and people who eat meat also argue that they eat healthy foods. The fact of the matter is that a healthy food needs good nutrition. In today’s society, people are very conscious about their bodies and their health in general. There are thousands of recipes and nutritional diets that are out there to help in keeping people healthy and being fit. What makes a healthy food is a balanced nutrition. Many people do not have the right nutritional balance in their foods, and this ...

Lately there is a fierce debate going on whether not the organic farming has the capacity to provide food for 6 billion people in the world. Organic farming is a form of agriculture which is more eco-friendly emphasizing on natural way of food production. Unlike conventional farming in which copious amount of fertilizers, insecticides and pesticides are used; organic farming relies on natural means like compost, manure and other natural sources of fertilizers which are not produced in a chemical plant (HDRA). Organic farming does not use any synthetic fertilizers or artificial means to control pests and weed. Instead it depends on ...

Abstract

The most widely used fossil fuel around the world is coal. This is a component that carries both organic and inorganic components and hence its combustion over the years has led to environmental problems such as acid rain and sulfur dioxide emission. To combat this eco-system problem several combustion methods have been introduced and one of the most efficient means that has come to the attention over the years as a significant way is the Oxy alkalinolysis. In the past, there have been various desulfurization processes, which have been introduced. However, most of them have not given excellent results are ...

Aluminium is produced from bauxite. Al2O3. This is referred to as Alumina, or aluminium oxide is extracted from the ore. After the extraction, electrolytic reduction process is used to transform Alumina to Aluminium. From every two tonnes of alumina, one tonne of aluminium is produced. The bauxite consists of ferrous oxide, titanium oxide, earth silicon, and alumina, approximately 40 to 60%. Bayer process is used to separate pure aluminium from bauxite (Habashi 16). This process involves heating the ore in an autoclave that contains caustic soda. Cooling then takes place, in order to separate the solid residue that is ...

Summary

Bayer CropScience is a pesticide producing company in West Virginia. It is independently operated company within Bayer Group, which is its pharmaceutical parent company with its headquarters in Leverkusen, Germany. The company operates in three markets, Bayer CropScience, Bayer HealthCare and Bayer Material Science. Bayer CropScience is a global provider of crop protection agents such as herbicides, insecticides and fungicides for both commercial and private use (Monheim, 12). On 28th august 2008, two workers were fatally injured when a waste tank having the pesticide methomyl aggressively blasted, destroying the Bayer CropScience chemical plant processing unit in West Virginia. The accident happened ...

Warfarin as used in medicine

Warfarin is a drug that serves as an anticoagulant; it is most commonly used in the medical field to prevent thrombosis which is the formation of blood clots and thromboembolism which is the migration of these clots to other parts of the body. It is also used in the management of deep vein thrombosis, arterial fibriation and pulmonary embolism.[1] This drug is a derivative of dicoumarol a 4-hydroxycoumarin-derived mycotoxin anticoagulant that was discovered in spoiled animal feeds that are made using sweet clover.[2] The recommended dosage is 10mg of warfarin for urgent anticoagulation, after that a maintenance dosage of 5mg ...

Introduction

Sigmund Freud emphasizes the importance of the psychoanalytic value of dreams tremendously. He is of the opinion that dreams give a useful insight into the unconscious mind of a dreamer. His fascination with dreams shows in his keeping a diary during his childhood and he has used many of the ideas and dreams written on the pages of his diary while composing his most famous publication 'The Interpretation of Dreams'. Freud believes that dreams are an attempt to fulfill wishes by the id, especially those wishes which remain unfulfilled in the waking life due to various reasons. Because the longings and desires ...

Political Science

An in Depth view of the Department of Homeland Security History of the Department of Homeland Security The Department of Homeland Security was brought about by the tragedy of the September 21 terrorist attack of the Al-Qaeda group. It was during this time the two airplanes purposely targeted to cause destruction of the Twin Towers in New York City and the Pentagon in Washington D.C. This event was regarded as the worst act of terrorism in America after the loss of 3,000 innocent lives. It was during this difficult time that the world grieved for America ...

Cocaine is an illicit drug that is made from the leaves of the coca plant. Cocaine can be manufactured in several. A common method involves copping the coca leaves and mixing this with ammonia and lime. Following this, the mixture is placed into barrels with diesel gasoline. The active component of cocaine dissolves into the gasoline and the gasoline is filtered out from the rest of the mixture that is discarded. Sulfuric acid is then mixed with the diesel mixture. This allows for the formation of cocaine sulfate. The cocaine sulfate is then mixed with more lime to neutralize ...

Requirement for the Manufacture of Drugs concerning Public Safety

Abstract The study will focus on pharmaceutical companies’ standard operation procedures. More in depth, the study will determine if cleaning validation and verification is a successful way to keep the quality of manufactured drugs at a high standard. The importance of the validation of a sterilization process will be examined. The study will list reasons for validation of sterilization through a set of regulatory expectations put in place by the FDA. The regulatory expectations of the FDA will support the methods and analysis used to conduct this study. The study will also examine the success and failure of cleaning validation through ...

Introduction

Pharmaceutical companies should create and follow a standard operating procedure by implementing a cleaning validation to ensure future patient safety. Validation has received great attention by the FDA in recent inspections. Manufacturers must validate their cleaning process to ensure compliance with GMP regulations 1. One of the main keys in the manufacturing of dosage formulation is to develop cleaning procedures that will remove all types of residues from the equipment and containers. The goal of Cleaning Validation is to ensure effectiveness in cleaning equipment, and to prevent pollution and cross contamination of drug products to ensure the quality, safety; efficacy and ...

Introduction

The social learning theory seeks to explain the development of antisocial behavior. Akers’ social learning theory is composed of four major concepts. They include differential association, reinforcement, imitation (modeling) and definitions. It postulates that people learn criminal or rather offensive behaviors in the same way they learn noncriminal/offensive behaviors. According to Akers’ theory, reinforcement learning involves getting rewards or punishments for criminal behaviors over time. As far as pro-criminal definitions are concerned, it posits that people who have definitions that favor crime or any other antisocial behavior have a high probability of getting involved in the crime(s) or antisocial ...

Prions are infectious proteins that are usually linked with the occurrence of neurodegenerative disorders in humans as well as many other mammals. They belong to the class of misfolded proteins and are the causative agents for the different transmissible diseases, mainly encephalopathy that can be defined by the changes in the anatomy accompanied by Pathophysiological origin that follow Mendelian genetics. The main characterization of the disease is the aggregation of proteins in the neurological system leading to degenerative brain diseases that are fatal and are incurable at present. Murray et al. (2004, p.37) have stressed that the transmissible ...

Mitochondria and Endoplasmic Reticulum

Literature Review

Literature Review - Interactions Between Mitochondria and Endoplasmic Reticulum and Mitochondria Calcium Dynamics The interactions between mitochondria and endoplasmic reticulum in plants have great significance in the ability of the plant to self regulate, grow well and even fight off toxins. Calcium is very important for strengthening cell walls (Holdaway & Helper, 2003). The dynamic of calcium up-take has been studied since the 1800s due to the importance calcium has as a regulator for successful growth and development of plants (Hepler, 2005). The intricacies of the part Calcium plays in intracellular reactions which regulate growth and development ...

Weather: Clear, warm, temp at 86 F (outside) and 68 F (inside)

Time: Arrived on scene at 2058hrs

This was in response to an emergency phone call at 2055 hrs, made by a female who was hysterical but managed to give precise location of incident. On arrival at house, I found an early twenties white female lying on the living room couch and she seemed traumatized and confused. I quickly assume she is the caller and it was later confirmed that indeed she was Miss Jaen Daugh. She was assisted from the apartment by my colleagues and taken to the ...

1. The admissibility of scientific evidence and expert testimony in court has been the subject of recent debate in both UK and USA. Briefly discuss the background and compare and contrast how courts in both Britain and America make sure admitted evidence is relevant and reliable.

Introduction

The courtroom, never an isolated corner of the societal landscape, has felt science’s impact. Over the years, courts have tried various methods to respond to the increasing influx of science. However, the problem of defining standards for admitting scientific expert testimony is one with a venerable history and in all likelihood, an enduring ...