A 1,000 – 1,500 word limit exists
i) What is the research question? In the treatment of patients with Kawasaki disease (KD), is the addition of corticosteroid therapy to standard therapy recommended over standard therapy alone? KD, an acute autoimmune disease that most commonly affects children and infants, results in the inflammation of the medium-sized blood vessels throughout the body. In rare and extreme cases, KD can affect the heart by causing coronary artery aneurysms and other abnormalities. Conventional primary treatment of KD involves the administration of intravenous immune globulin (2 g/kg) and aspirin (80-100 mg/kg) each day until fever subsides. Newburger et al. (2007) have ...