Essays on Retroviral

For this assignment, I have selected HIV/AIDS as the health issue and the country I have selected is Sub-Saharan Africa. 39% of the adults in Sub-Saharan Africa are on retroviral therapy. Swaziland in Sub-Sharan Africa, is the country that has the highest prevalence of HIV/AIDS in the whole of Africa and also the world. The prevalence of HIV/AIDS is 27.4% (AVERT, 2017). The total population in the country in 2015 was 1,287,000. In addition to HIV/AIDS, the country is also troubled by other major health issues like Malaria, Tuberculosis, Malnutrition, Alcoholism and Tobacco Use. The population growth ...

Abstract

Over thirty years after its identification, HIV and AIDS remains a somewhat elusive virus, particularly when it comes to its history as a human infectious agent, and resourcing a complete epidemiology of the disease. Part of the problem is that so many antiretroviral drugs have come out and have either been used or prescribed incorrectly. In addition, the virus, like many other reverse RNA transcriptase viruses, has a very high aptitude in terms of developing resistance to drugs at a very rapid rate. What further complicates matters is how quickly it has spread. It will probably never truly be ...

Bladder cancer has been shown to respond to therapies focusing on the immune system and may thus represent a good candidate for the use of retroviral models designed to encode for antitumor genes associated with the immune system, such as the ProT gene. ProtT stimulates T cell formation and suppresses the development of tumors. In an animal study, Shiau et al evaluated the efficacy of prothymosin alpha (ProT) as gene therapy for the treatment of bladder cancer. The researchers created a recombinant retrovirus carrying the ProT gene and injected it into mice along with bladder cancer cells. The mice on which ...