Essays on Sickle

Introduction

Sickle Cell Anemia or Sickle Cell Disease is an inherited blood ailment. Those suffering from Sickle Cell Disease have abnormal S/ sickle hemoglobin in the red blood cells. Hemoglobin is the protein in the blood that aids in carrying oxygen throughout the body. The ailment takes its appellation from the shape of the red blood cells of a person affected by Sickle Cell Disease, which have the shape of a sickle. They are stiff and adhesive rather than a disk like normal cells. The misshapen cells tend to get trapped in the small blood vessels hindering the movement of ...

Abstract

In the last century, the knowledge of molecular biology has increased, opening new opportunities for addressing different diseases that have been affecting all populations. Before, genome and proteomic studies were seen as complicated field due to inability to get significance understanding of disease components at the molecular level. However, with the expansion of molecular biology, different techniques and tools have been developed to aid diagnosis and treatment of diseases. In this study, these tools have been investigated to understand how the knowledge on molecular diagnosis helps in detection and treatment of diseases. This study focused on the application of ...

Historical Background

Despite gender selection going back to our earliest societies, the history of gender selection in human embryos is relatively short. Gender Identification was first made possible in the 1970’s with the advent of technologies such as chorionic villus sampling (CVS) combined with ultrasound. This early method of sperm sorting has an average cost today of $400-600 More recently in the 1990’s the ability to reliably sex embryos for in vitro fertilization (IVF) has been the basis of the media focus on gender selection in human embryos. In 1995 clinical trials to achieve FDA approval, of this second ...

Modern technology is one of the fastest growing economic rates in the country and workers at health sector need to be trained for them to be well equipped with the knowledge and skills for its operation. The changes, for example, were formed to reduce the number of hand-written reports that gave false information about the illness of some patients and ensured that the staffs update all medical information data in an accurate way for easy reference by any patient caregiver or the doctors. The administration at health facilities is required to ensure that the technology used to offer services ...

Coursename Sickle-cell anemia is a genetic blood disorder, which affects the red blood cells. It was first described in the medical literature in 1846. In 1910, Ernest Irons became first to write about the pathologically altered red blood cells of the patient with sickle-cell anemia (Serjeant 425-429). It is caused by the mutation of the gene encoding the synthesis of the hemoglobin. As a result, the hemoglobin of the affected people is defective (hemoglobin S). Glutamic acid in it is substituted with valine in the sixth position of the β-chain. This change greatly reduces the solubility of hemoglobin in ...

Abstract

Sickle cell anemia is a hereditary disorder in which the red blood cells, which function as the oxygen carriers throughout the body, develop in an abnormal manner. The red blood cells are normally disk-shaped and very flexible but in sickle cell patients the cells often become very rigid and crescent shaped. This abnormality in the shape and functionality of the red blood cells hinder the normal flow of blood in the body. The red blood cells are therefore rendered unable to move freely through the blood tissues and through organs that result in the failure of certain important organs ...

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Sickle cell anemia is the most widely inherited genetic disorder in the United States. Folic acids are one important nutrient that helps increase and produce some red blood cells in the bone marrow. This paper investigates how folic acid has used a supplement for pregnant women (Knott). Sickle cell anemia can be genetically passed to the baby from a mother who has it or who is a carrier. Symptoms of the disease include headaches, irritability, fatigue, dizziness, diarrhea, cold feeling, difficulty when breathing, difficulty concentrating and pale skin (Lindenbaum, John, & Klipstein 16). Malnutrition in pregnant females is the main ...

Sickle cell anemia is the most widely inherited genetic disorder in the United States. Folic acids are one important nutrient that helps increase and produce some red blood cells in the bone marrow. This paper investigates how folic acid has used a supplement for pregnant women. Sickle cell anemia can be genetically passed to the baby from a mother who has it or who is a carrier. Symptoms of the disease include headaches, irritability, fatigue, dizziness, diarrhea, cold feeling, difficulty when breathing, difficulty concentrating and pale skin ( Lindenbaum, John, and Klipstein ,16 ). Malnutrition in pregnant women is the commonest ...

Sickle cell anemia is a genetic disease, passed on from parents to children along the generations. It is a condition which causes severe pain and anemia. It happens when the body lacks healthy red blood cells to circulate oxygen in the body. The usual shape of the red blood cells is round, and they are flexible so they can pass through the narrow blood vessels of the body. However, sickle cell anemia causes them to become sickle-shaped, like tiny crescents, which are sticky and inflexible. This restricts their movement in the blood vessels causing them to get stuck in ...

1.0 Introduction Serological blood grouping has been used successfully for decades to ensure safety in blood transfusion. However blood incompatibility continues to be a significant challenge in transfusion medicine reflecting the inherent limitations of the hemagglutination based serological blood typing. Some of the limitations of serological blood grouping include weak reactivity of some antibodies that are clinically significant; weak expression of some red cell antigens; the subjective nature of the available tests and lack of universal methods of detecting and identifying antibodies. In addition there are several issues related to the reagents used which include the wide variability of ...