Essays on Suspension

Caucasian and African women are segregated by the differences in their salary and education. With the persistence of racial-based wage and education gaps in modern society, the status and role of colored women, specifically those from the African descent, remain discriminated due to the prevalence of indissoluble racial and gender stereotypes. Although the philosophy of racial and gender equality has, in essence, created “equal education opportunities” for all females, the provision of racial equity has yet to be fully realized. In reality, however, the education and economic gap between Caucasian and African women evinces that the school and professional ...

Introduction

BMW Group is one of the most successful automotive companies in the world and is a considered a brand leader in the premium market segment in the United States. Despite competitive pressures within the market segments and among the low and mid-priced automotive, BMW’s vehicle volume sales continued to increase by 5.2% in 2015, thanks to the normalization of the global economy. Its revenues also increased by 14.6% and reached $92.2 billion while its net income reached $6.4 billion, a 10% increased from the previous year (BMW Group, 2016). As per location, Germany accounted for 42.6% of the ...

I. The Prosecution’s Offer The first step in making a plea offer is looking into Mario’s criminal background and the specific facts of the particular case. For instance, if Mario had and extensive criminal record including multiple DUI arrests of convictions, then the pleas offer would probably not include much of a choice other than pleading guilty and accepting a sentence of 364 days in jail, completion of a treatment program, and 2-3 years of supervised probation; or 2-3 year in prison. However, assuming that Mario does not have an extensive criminal record or DUI history; a ...

Horse-run carts portrayed the streetscape right up until the commencement of the previous century, but the arrival of the vehicle, which Carl Benz and Gottlieb Daimler created separately of one another in the year 1886, instituted a totally fresh combination of needs as compared to those connected with horse-run carts – particularly where the suspension was a concern: it was essential to handle superior pace, without jeopardizing road travelers. Carl Benz and Gottlieb Daimler assumed dissimilar approaches to this issue: while Benz chose the cycle as the initiating point for his Copyright Motor Car and employed a navigating head plus ...

Dear _______,

I am writing you to give my explanation regarding my failure to successfully complete all of the requirements for re-admission to the School of Social Work’s undergraduate program by the deadline of May 1, 2016. After my suspension from the School of Social Work, I felt that I needed to spend the summer of 2015 taking care of both myself, and my family. During my last semester at the University, my nephew was a victim in a homicide. I was responsible for the planning, and final expenses of his funeral. During this time, my husband and I adopted ...

Emma Williams’s Case

Arbitration is a formal process for determining a grievance between parties in a conflict. A labor arbitration process involves an employment-related dispute between an employer and employee. The authority of an arbitral award comes from the binding arbitral clause in a contract of employment or the authority given by the parties through the appointment (Walras, 2013). An arbitrator has quasi-judicial powers to investigate, listen to the grievances of the parties and provide a decision, which is binding on all parties involved in dispute. However, arbitration must be launched on time to have a force of law. The dispute in ...

The institutional affiliation

Amazon.com, Inc. is considered as the leading e-commerce retailer in the United States possessing over $70 billion revenue in 2015. The company maintains a lean focus on increasing its operating income by constantly raising its revenue and managing its working capital and expenditures. Thus, the Amazon’s customer base demonstrates a constant increase, mainly because of the low costs; however, prices are not the sole contributor to its success (Becker, Uhr, Vering, & Ehlers, 2001). Amazon pursues a concentration strategy in which it uses the Internet as the major distribution channel. Well-organized product information and sophisticated algorithms make the shopping ...

My previous education experience was not very positive and resulted in my academic suspension due to a number of facts which had made me to change my priorities for that period of time. The matter is that while I was living in another state far from my family, my niece got sick and subsequently operated. Since my brother-in-law was not available at that moment being out of the country, I had to constantly travel to visit my niece and support my family. Unfortunately, owing to this stressful situation, I was always depressed and disconcerted in my academic work so ...

and Classical Conservatism in the Modern Period

Introduction

Classical Liberalism and Classical Conservatism emerged as political philosophies from the past centuries as guides for government ruling. While liberalism aims for equality, conservatism wanted natural hierarchy. These two conflicts were mainly headed by two different minds in the person of John Locke (Liberalism) and Edmund Burke (Conservatism). However, no matter which became more favored in the past, the application of these ideologies in the present time is considered to be more complex than before.

Body

Take the current educational policies as considerations. Today, there are many aspects to be considered in schooling ...

Introduction

Adolescence is a time when a person’s physical, psychological, social and cognitive growth is of great importance. During this time, the person is not a child and they are not yet an adult and some of the choices made at this time in regards to their health, lifestyle, and attitudes can be continued into adulthood. People in this stage are greatly influenced both academically and socially by social interactions. Some relationships established in academic institutions with peers and authority figures are said to be major socializing agents, especially for middle school students. Even though school is considered a ...

Fuel Cell Technologies in Passenger Cars

Fuel Cell Technology The last decade is characterized by the rapid development of research activity in the field of fuel cells, thus, creating the conditions for their uptake in electric systems. The basic fuel cells’ operating principle has been known for 150 years. However, a variety of technical and financial problems had kept them on the margins of technological applications (Brandon & Hart, 1999). The basic difference between a fuel cell and batteries is that while batteries store energy, fuel cells directly convert a fuel’s chemical energy into electricity by an electrochemical reaction (i.e. Without requiring combustion or movement ...

Role of Cyber Speech and First Amendment

The Internet has transformed communication throughout the world, allowing people to share information instantaneously at relatively low cost. The Internet is regarded as the most participatory form of mass speech ever developed in the world and it is the main channel of communication that is behind the development of cyber communication. Students in schools and colleges communicate amongst themselves through social sites such as Facebook and Twitter. They can receive first-hand information that has not even reach their school administration. More often, students use these sites to express their feelings about politics, school administration, and relationships. Most of them ...

Introduction

Alternative sentencing makes way for committers of minor crimes and those with no criminal records to transform and comply with varied ethical standards as laid out by the state. With enhanced supervision as an alternative to incarceration, court administrators are involved in monitoring activities such as substance abuse treatment, random drug testing and community services performed by the offenders. The probation officers have to work closely with the Office of Community Corrections to ensure that the benchmarks set by the judges are met and that the offenders are able to contribute to long term growth and stability of the ...

What nursing interventions are appropriate for Mrs. J. at the time of her admission? Drug therapy is started for Mrs. J. to control her symptoms. What is the rationale for the administration of each of the following medications? 1.IV furosemide (Lasix) 2.Enalapril (Vasotec) 3.Metoprolol (Lopressor) 4.IV morphine sulphate (Morphine) Lasix is used to reduce fluid retention that occurs as a side effect of heart failure. It is additionally used to treat hypertension and lessen effect such as the shortness of breath, swelling of limbs and the abdomen. It is used as an IV to treat the immediate consequences of ...

Human Resource Management

Rights of Workers and the Consequences of Unfair Labor Practices The National Labor Relations Act (NLRA) was enacted in 1935 by the Congress to protect the rights of both employers and employees, to encourage collective bargaining and prevent unfair labor practices that may harm the welfare of workers and the country’s economy (National Labor Relation Board, 2016). The NLRA assures employees of the private sector the rights of being able to organize into trade unions, participate in collective bargaining to champion for better conditions at work and better terms, and take collective action (strike) when necessary. Under the ...

Many a time have people heard about politicians who do plenty of talking. However, verbal rhetoric is only meaningful when backed by actual deeds aimed at the improvement of what politicians oversee, which is society and its welfare. The incumbent Senate President of New Jersey, Stephen Sweeney is one of such politicians who may be said to utilize his legislative authority to its limit. He has showed his aptitude in areas, such as education, property ownership, taxation, healthcare, and the protection of different social categories. Of course, as with other prominent politicians, however renowned, Sweeney has made some controversial ...

Mary Bell is one of the well-known young killers. She was accused of the death of Brian Howe and Martin Brown. The details of the murders were gruesome, including the strangulation of one of the victims who was a three-year-old boy. Mary's family background is said to be responsible for her delinquent behaviors. Firstly, she thought that Bill Bell was her biological father (Calin, 2011). Billy was a criminal arrested for armed robbery and her biological father was unknown to her. Secondly, Mary claimed that her mother, who was a prostitute, had forced her to engage in sexual acts ...

Introduction

Suspension bridges connect roadways between two land masses by links, ropes or cables hung from two large towers. These towers bolster most of the weight as pressure presses down on the deck of the suspension bridge and after that goes up the links, ropes or binds to transfer pressure to the towers. These bridge towers then disseminate the pressure directly to ground. The metal links on the suspension bridge, then again, have to bear all the bridge’s tensional forces. These cables are suspended across level planes between the two widely separated anchorages. Span docks are basically strong rock ...

Introduction

Even though the concept of evolution is a typical narrative, it remains one of the most highly contentious of the topics. Major disagreements persist in the field, particularly when the evolutionary origin and physical modification of primates are the subject matter of discussion. Because of these differences, lots of significant finds in the field have attracted considerable amounts of opposition from experts depending on the species, or the side angle of evolution one recognizes (Ravosa and Dagosto). Disputes often center around locomotion and posture – whether a particular species was fully upright or could walk bipedally, brain size (intelligence), sexuality ...

INTRODUCTION

Klebsiella pneumoniae belongs to Klebsiella species of Enterobacteriaceae and constitutes the normal flora of the human mouth and intestine. K. pneumonia is the most predominant and clinically critical organism. Infections with K. pneumoniae are mostly contracted from the hospitals and principally occur in patients with damaged host defenses. The objective of this study is to perform techniques to identify the bacterium in the given sample and confirm its presence by staining and microscopic analysis.

Streaking may be performed on the clinical sample using Mac Conkey agar or blood agar with the goal of isolating colonies of the organism from ...

Abstract

Transformation remains, and hugely significant tool in extending the borders of life sciences and medicine. It can be referred as fixing intracellular DNA into a bacteria or organism through the vector, thus transforming it. This paper uses plasmid pUC18, self-reproducing circular/spherical strands of genes that may be modified. After the bacteria absorb the vector, some proteins not usually synthesized will occur. In this study, a system has been developed to monitor the transmittance of different DNA (genes) from a genetically transformed strain of Saccharomyces cerevisiae to E. coli. This mechanism is centered on yeast strains that contain several integrated ...

A brake is a device that produces artificial resistance to the moving part of a machine to stop or slow down its motion. Any machine or its part that is in motion possesses kinetic energy. As per physical laws, energy cannot be destroyed; its form can only be transformed. The brake system converts the kinetic energy of the moving machine or part into thermal, potential or chemical energy. Brake systems are of various types utilized in different applications in industries, home appliances, vehicles, railway trains, and other sectors. This paper has focused on the brake systems used in vehicles, ...

Panther I.D.:

“The expression of ampicillin resistance and luciferase enzyme genes by E. coli transformation using the pUC18 and lux plasmids” Abstract The transformation process allows the uptake of DNA from the environment, with the incorporation and expression of genes. During this process, changes in the DNA of the receptor cell occur, producing some selective advantages in some cases, such as resistance to antibiotics. pUC18 and lux plasmids were used to determine the transformation process in Escherichia coli. Cells were made competent by the addition of calcium chloride and heat shock in order to induce the incorporation of the ...

Wheel alignment refers the process whereby car wheels are adjusted to the optimum standards recommended by the manufacturer. We adjust alignment angles using sensitive computerized equipment to the desired angles, but they can be adjusted beyond to achieve the required specifications. Incorrect wheel alignment results in some undesired effects. The wheel alignment will reduce tire wear and for the car to travel in a straight line (Pacejka, 2005). Suspensions are made of springs, shock absorbers, tire air, the system of tires and linkages that connect the vehicle to the wheels and allow motion between the two. Suspensions contribute to ...

Did Human Bipedalism Evolve from a Knuckle-walking Ape Ancestor Did Human Bipedalism Evolve from a Knuckle-walking Ape Ancestor

Introduction

The narratives of human evolution are one of the oft-told scientific stories whenever the topic of the origin of man crops up. However, this topic is also one of the thorniest and most highly contentious. There are major disagreements in the manner in which man first came to be, and every interpretation of almost every new find on the matter will be sure to find opposition among scholars on the field (Harcourt-Smith & Aiello, 2004). While there are numerous causes of disputes ...

Chemistry

2. The nano carrier needs to remain in suspension in H2O, PBS, human serum, etc. What type of polymer do you need to use to decorate the surface of the nanocarrier to achieve this goal? In order to maintain the nanocarrier in suspension in water, Phosphate-Buffered Saline (PBS), human serum a suitable solution a polymer is needed on its surface. The polymer used needs to accomplish three goals. The polymer needs to decorate the nanocarrier surface to enhance suspension and secondly, to prevent protein absorption. Another characteristic is that the polymer evades the immune system. PLGA poly(lactic-co-)glycolic ...

The Court of Appeals should reverse the district court’s decision, and grant to Ms. Eriksen a motion for preliminary injunction, because Ms. Eriksen engaged in constitutionally protected free speech. This case encompasses the violation of First Amendment rights and this court ought to “conduct an independent examination of the record as a whole, without deference to the trial court.” Bery v. City of N.Y., 97 F.3d 689, 691 (2d Cir. 1996). For the First Amendment issues, the appellate courts must make an independent inspection of the whole record in order to ensure that lower court decisions do not ...

Introduction

Drunk driving is still a major problem in several parts of the world. Even though most of the countries penalize offenders by having their car license suspended, the accident rate is not decreasing significantly (Wald, 2006). This is because even if a person’s license is suspended, he can still be able to drive a car as long as he will not be apprehended by the authorities. Because of the ineffectiveness of such regulation, authorities nowadays have been finding new ways to reduce the occurrence of drunk driving, and consequently, reduce the number of related accidents. One potential solution ...

The paratransit sector offers complementary services to those of traditionally fixed route rail and road public transit systems. Taxis have traditionally been a major segment of paratransit services. Disruptions brought about by technological advancements, and the increasing clamor for the sharing economy poses a threat to traditional paratransit service providers. The most prominent of these technological disruptions include Uber and Lyft, which are taxi-hailing apps. These new initiatives face opposition from traditional taxi operators. Debate still rages on whether they create more jobs in the industry and the economy as a whole or they result in a net loss ...

The scenario at the Anytown High School has proven that a lot should be done in order to deal with the issues of bullying in the school fraternity. It has proven that the students that get bullied by their fellow students undergoes great deal of stress and can do anything to avoid being bullied. The deputy principle did a great job when he managed to stop one of the students from actually shooting his fellow. The school board then decided to come up with policies to curb this behavior and avoid problems that could have arisen from this. The ...

Within our constitution we have the privilege of utilizing the first amendment. As American citizens, we are allowed to speak our minds on things that matter to us. In this paper, I will review the classic free speech case study of a student going against the desires of the reigning student administration with undesired results. In this essay, I will argue that the school went too far in their claims against the student’s freedom of speech. When Littleton High School student, Bryan Lopez, posted unfavorable comments on his MySpace page regarding his school’s deteriorating conditions and biased ...

Studio recording design

For the design of the acoustic of the room, there are theories that have been put in place to ensure that the quality of the final sound was superb. The sound acoustic methods that analyze the effects of sound sources that are present in the room can be described is the geometrical, the statistical and the adulatory theories.

The geometrical theory

This theory is used to determine the points of incidences of the rays at the bounding room surface. It is paramount since the theory is also used to determine the losses of energy that is caused by the absorptive materials that ...

ABSTRACT

Coffee is an important cash crop in the world market. It fetches a lot of money for those who engage in the coffee business. Over the past few years, there has been a change in coffee prices. Sometimes they are high while at other times they are very low which is similar to other commodities traded in the international market. This write-up contains factors that affect changes in commodity prices, specifically coffee. Among the factors identified are market forces of demand and supply, speculative effect, climate conditions, and geopolitical factors. The key participant companies in the coffee trade are ...

We can notice Phantom series quadrocopters produced by Chinese company DJI at almost every mass event. Phantom 3 Standard is not just another toy with the ability to be connectedd to a smartphone, but a device that can be both fun, hobby, and even be used for professional purposes. High-quality camera, a great range of action and the ability to raise to a height of 500 meters, convenient operation, modes for beginners and professionals – all these features make Phantom 3 Standard the best choice for those who are willing to spend not rather huge money for pioneering the sky. ...

Impaired driving remains a crucial social problem in Canada and around the world. Under the Ontario driving regulations, impaired driving implies operating an automobile while under the influence of alcohol or drugs. It is considered an offence and may attract charges such as loss of license, vehicle impound, administrative monetary penalty, fine if convicted, and some jail time. The Canadian army of Mothers against Drunk Driving estimates that between 1200 and 1500 people die every year from alcohol and drugs related accidents. In Canada alone, impaired driving affects close to 70,000 individuals every year (InsuranceHotline.com).

Drinking and Driving

The effects of ...

Introduction

Social work is a profession that covers wide facets of the community by addressing the needs of individuals and their families, specific groups such as the elderly and children as well as the entire community as discussed by Dominelli (2009). More particularly, it is oriented to making their clients self-reliant by building of capacity through training, community enlightening and group empowerment. Additionally, the responsibilities of the professionals may target the vulnerable groups within the community to reduce the harm that may come upon them through sponsoring their educations and informing on the potential risks as well as the ways ...

Youth with Disabilities Problem

Introduction Current issues and statistics of the juveniles experiencing disabilities and their disproportional representation in the juvenile justice system. The attitude of the educational system towards the disabled students and the role of the teachers in the process. Legislation, enforcement and advocacy regarding the problems of this group of children. The role of the police and other enforcement authorities in cases with disabled juveniles that commit minor offences. Recommendations. Conclusion INTRODUCTION The White Paper discusses the current situation with the system that disproportionately targets juveniles with disability problems in regard with School-to-Prison Pipeline. What is a school-to-prison pipeline? This ...

New theoretical approaches to the study of history have led to a major shift in the way we perceive political history leading social scientists to question the findings based on the old approaches. The new approaches have revolutionized our study of history, further proving that history in itself is not merely a study of the past but is also a living art subjected to the changes that occur within those affected by it. These new approaches have evolved perhaps due to the need to ensure that even generations that did not partake in the major historical events of the ...

Investigating how light intensity will affect the rate of photosynthesis, with the help of DCPIP, in Spinach leaves.

The aim of this experiment is to find out how the rate of change of light intensity affect the photosynthesis in spinach leaves. Successful farming of food crops is very essential for both the nutritional and financial health of a nation. Governments of almost every nation invest land and labour to crop farming, as much as is possible, keeping in mind the other needs of a country. But, however, due to many reasons the maximum crop yield possible is not always achieved. For the production of a healthy crop certain conditions are necessary. The primary among these conditions are ...

The institutional affiliation

Dear Mr. (Mrs.) XXX, I am herewith writing this letter to appeal my academic suspension from the School of Nursing. Even though, I regularly attended almost all classes, I failed on my exams in XXX and XXX and was dismissed due to the poor academic performance. I was not surprised, but still very disappointed to hear this news. Thus, I would like to ask you to readmit me to the school and allow me to continue my studies next semester. My busy schedule at work did not allow me devote enough time to my studies; thus, my results, as ...

Introduction

There have been incidents of employee fights and incidents at Acme Manufacturing which is a Fortune 1,000 company. The General Manager (GM) informed the Human Resource manager about an occurrence that occurred in the last week that requires immediate attention. The company's manufacturing operations are carried out in three shifts thus the plant operates for 24 hours every week. In the last six months, there have been hostilities between the employees that work the third shift and those that work on the first shift. The hostilities started with criticism and jeering by the workers on the first shift ...

I would prefer to share the experience of my friend when he worked in a certain company, a department store, three years ago. He was new in the company and was assigned in the logistics department. Unfortunately, he had a misunderstanding with his co-worker, a team leader, who has been working with the company for about five years. The misunderstanding was about the wrong delivery. The team leader confronted my friend and blamed him and not allowing him to explain the real scenario. The situation caught the attention of the supervisor. My friend was requested to come to the ...

I attended SAE Formula sessions which usually takes place on Wednesdays 4 pm where I learned quite a number of practical lessons. The first session took place on Week 3, 28 Jan 2015. We learned about the chassis. The design problem faced were that the main roll hoop was not rule compliant while the new one ordered was expected to arrive Jan-29th. Meanwhile we decided to tack the new role hoop onto the chassis and begin assembling the suspension components for rolling chassis. On the suspension part we realized that the silver horse was not matching with the piece ...

P and I Rule Book. According to the American P and I Club Rule Book, there is a clause about claims that are payable at the discretion of the Directors. Section 20 of the Rule book, titled “Ominbus” clause outlines that there may be circumstances where the Directors may choose to pay on claims that they collectively decide should be paid.

If the liability is not excluded elsewhere in any of the previous nineteen clauses, then the Directors can choose to pay a claim. This seems to be a fair way for the organization to establish that there may be unusual ...

It has come to my attention that there are rumors going round the company and the town that there were incidents of food contamination in plant and that some of the employees attempted to cover up the incidents. The rumors further allege that employees have been intimidated into reporting the irregularities to the senior management. It alleges that these employees attempted to bribe food inspectors from the Canadian Food Inspection Agency. Mr. Smith and Mr. Bush, who are floor supervisors, have been substantially mentioned in the allegations as the main perpetrators.

These rumors are spreading fast and can cause a ...

Malaysia is internationally recognized for its economic performance and the currency crisis it went through in the year 1997. Malaysia is seen as a success story and recognized for its successful management strategy. Prior to the 1997 economic crisis, Malaysia had experienced a recession in the 1980s that led to a negative GDP in the year 1985. Malaysia, however, reversed this negative growth by the year 1987. Malaysia proceeded to grow economically from 1987 through the 1990s up to the year 1996.

In the year 1997, the currency crisis hit the country though it still recorded economic growth in GDP. From ...

Expulsion Structure

According to the CPS policy manual adopted in 2010, expelling students is divided into two categories: expelling students with disabilities, and those without disabilities. Expulsion is done through a hearing when a student has served a mandatory suspension of 10 days. After a hearing, the expulsion ranges between 11 days and 2 years for each incident. Non-disabled in CPS can be expelled due to: fighting, kidnapping, bullying, arson, violence, bomb threats, gang activity, and stealing. Disabled in CPS can be expelled due to the same reasons but if the offense is due to disability, then there would be no expulsion for the students.

Control of Structures and Decisions

...

I am an international student in Vancouver, Canada, and I have been in the country for two ...

Discussion #1: Nurse Practice Act and Rules and Regulations in Texas Board of Nursing

Sec. 301.451: This section sets the precedence upon which the Texas Board of Nursing can take disciplinary action against an individual for reasons that have been proven beyond doubt that they would in one way, or another compromise the delivery of service. This section identifies all prohibited practices within the health care settings for all nurses. Among the issues, it identifies include the use of fraudulent documents or those obtained unlawfully by anyone serving within the workforce. The section also identifies the use of a license that has been revoked or suspended as a prohibited practice (Texas Board of Nursing, ...

Assignment 1

In my previous paper, I outlined some of the encounters that I can describe as defining moments. As a matter of fact, a defining moment is any instance that in one way or another affects the life course of a person. Apparently, the defining moments as narrated before were the meeting with the motivational speaker, and the unfortunate squabble between my best friend and me in our adolescent days. Clearly, of these encounters the former was quite inspiring and constructive. On the contrary, the latter was characterized by adversity because after the encounter, I was regretful, stressed out and shamefaced. These feelings ...

Introduction

Many school officials have performed countless duties and responsibilities in different level of challenges that are extremely in demand. School officials are expected to work hard with different students with different characteristics, faculty, and parents in complex circumstances. It is necessary to face multiple needs and the necessity to make decisions in accordance to the environment it belongs, in the right time, right management, and with full liability. In the legal research, the importance of the Supreme Court about the New Jersey v. T. L. O. is reviewed properly by state court cases related to the Search and Seizure ...

Introduction

Misconduct is an unacceptable behavior that goes against an organizations laws and regulations. Hence, employee misconduct is a violation of the organizations set rules by an employee. On the response to the employee misconduct, the employer should be familiar with how to handle these instances to avoid recurrence. Occasionally, it is important to introduce a disciplinary committee that will deal with employee misconduct. The human resource manager is responsible for employee misconduct handling and taking necessary actions (Dempsey, 2010). There are many types of employee misconduct such as;

- Excessive tardiness or absences - Insubordination - Rudeness and abusive ...

The Airline Pilots Association or ALPA have entered a collective bargaining agreement with Northwest Airlines in behalf of the latter’s pilots. ALPA representing the pilots of Northwest in the bargaining agreement filed suit against the latter and brought in to the District Court claims for monetary relief and declaratory assertion of breach by Northwest on certain provisions of the pension plan and Employee’s Retirement Income Security Act of 1974, 29, U.S.C. §§ 1001 (law.cornell.edu, N.D., a). For twenty years Northwest Airlines Inc. had made arrangements on the collective bargaining agreement of its pilots through ALPA. Prior to August ...

Glade Bender JL, Lee A, Reid JM, Baruchel S, Roberts T, Voss SD, Wu B, Ahern CH, Ingle AM, Harris P, Weigel BJ, Blaney SM. Phase I pharmacokinetic and pharmacodynamic study of pazopanib in children with soft tissue sarcoma and other refractory solid tumors: a children's oncology group phase I consortium report. J Clin Oncol. 2013 Aug 20;31(24):3034-43.

This study describes a phase I clinical trial of “Pazopanib” in pediatric patients suffering from soft tissue sarcoma (STS). Pazonapib is an anti-angiogenic drug. It is a competitive inhibitor of ATP molecule1,2. It competes with the ‘substrate’ ...

In his 1996 State of the Union speech, President Bill Clinton stated, “If it means teenagers will stop killing each other over designer jackets, then our public schools should be able to require their students to wear school uniforms” The topic of whether or not school uniforms are a good idea in high schools is still a topic that is hotly debated. Some parents are happy about having a school uniform so they do not have to argue with their children about what they can or cannot wear to school. Some parents think that schools that insist on school uniforms are ...

Introduction

The tongue is comprised of small chemosensory receptors which detect different tastes such as sweet, sour or bitter. The information from the receptors is conveyed through the facial nerve, the glosspharyngeal nerve or the vagus nerve. The masking of the taste of the drugs is often done for several reasons. Key among these reasons is to avoid irritation of the stomach and the gut in addition to prevention of inactivation of the drug once it gets to the stomach.

The taste masking technologies can be grouped under three major categories which are: novel technologies, physical barriers, solid dispersion and ...

Introduction and Background

There has been a lot of evidence that working on health benefit and environmentally friendly projects may have both healthy and economic advantages. In itself, such projects have a positive influence on physical and emotional well-being and health of individual’s. However, essentially the possibility is to have an impact on single representative health which entirely relies on the attributes of the environments that may be universities, industries or other areas. This impact is applied through a few distinct ways amongst individual’s/students: 1. The nature of the exertion as far as demand and control is concerned. 2. The impact ...

Abstract

Experts tell that the twentieth century was the century of brutal man-made natural and environmental disasters. Often, we hear reports about falling missiles, planes, explosions on environmentally hazardous industrial objects, about the collapse of buildings. The main reasons of these tragedies are design errors related to insufficient knowledge of the laws of mechanics with the incorrect use of mathematical models. To prevent new disasters, we just need to look into the past and draw conclusions on the basis of the occurred accidents. Tacoma Washington Bridge Disaster (1940) Suspension bridges have a number of advantages in comparison with the ...

The renowned Steel Bridge is a double deck structure that has a vertical-lift and is also known as through-truss. It goes across the Willamette River in the city of Portland in the United States and was opened in 1912, so it recently celebrated its 100th anniversary. The bridge has the dual function of carrying rail and bicycle traffic on its lower deck whilst the upper deck is dedicated to road traffic. This innovative arrangement makes the bridge extremely innovative and the fact that it has an independent lift continues to emphasise its prominence as the second oldest vertical lift bridge in ...

Antifungal Medications

In dentistry and oral care medicine, antifungal medications are prescribed less compared to conventional analgesic or antibiotics. However, it is mandatory that a clinician or dentist is familiar with common antifungal indications and medications available in the market. Antifungals are used to treat oral candidiasis. Oral candidiasis is known to cause complex oral health problems. Oral and pharyngeal candidiasis is caused by the primary fungal organism Candida albicans. Oral candidiasis is listed as an acquired immunodeficiency syndrome by the Centers for Disease Control and Prevention. Due to imbalances in the oral flora, patients using oral antibiotics could develop case of ...