The article titled “The biology of cancer testis antigens: Putative function, regulation and therapeutic potential” gives an account of Cancer Testis Antigens (CTA) and their presence in human tumors of distinct histological origin. CTA are reliable for the administration of immunotherapeutic approaches due to their restricted patterns . Several clinical trials have already been conducted for the development of CTA-based vaccination therapies. Researchers were able to discover over 70 families of CTA from 140 individuals worldwide. According to the authors, while it is possible to extract a majority of the CTA during the process of spermatogenesis, the core function of ...
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Abstract
Testicular cancer is a type of cancer that directly involves the main male reproductive organ, the testes. The testes are basically a loose sack of skin and flesh located below the penis. Testicular cancer is a rare form of cancer only accounting for between 1% and 3% of the total number of cancer cases in the male population in western countries. It is also one of the most curable forms of cancer. Nonetheless, it is still a condition worth reviewing. The research question in this paper asks whether survivors of testicular cancer indeed suffer from a testicular cancer-related comorbidity ...